CAJ | 학술논문

目的：观察黄芪建中汤加减治疗消化性溃疡的临床疗效，及探讨其可能的作用机理和其相关副作用。方法：选取来我院消化科就诊的慢性十二指肠溃疡患者60例，随机分为实验组和对照组，各30例，实验组给予黄芪建中汤减去大枣加味山药、茯苓治疗；对照组给予奥美拉唑治疗；观察疗效并随访，纪录副作用情况。结果：实验组有效率为96.66%，对照组有效率为63.33%，差异具有统计学意义（P<0.05）；实验组出现副作用总数为1例，对照组出现总数为9例，差异无统计学意义（P>0.05）。结论：黄芪建中汤加减治疗消化性溃疡疗效显著，副作用较少，可能降低远期复发率，临床中疗效值得认可。
목적：관찰황기건중탕가감치료소화성궤양적림상료효，급탐토기가능적작용궤리화기상관부작용。방법：선취래아원소화과취진적만성십이지장궤양환자60례，수궤분위실험조화대조조，각30례，실험조급여황기건중탕감거대조가미산약、복령치료；대조조급여오미랍서치료；관찰료효병수방，기록부작용정황。결과：실험조유효솔위96.66%，대조조유효솔위63.33%，차이구유통계학의의（P<0.05）；실험조출현부작용총수위1례，대조조출현총수위9례，차이무통계학의의（P>0.05）。결론：황기건중탕가감치료소화성궤양료효현저，부작용교소，가능강저원기복발솔，림상중료효치득인가。
Objective:To observe the clinical curative effect of Huangqi Jianzhong decoction on treating peptic ulcer, and discuss the possible mechanism and its related side effects. Methods:60 cases of chronic duodenal ulcer were divided into two groups randomly, 30 of the experimental group and 30 of the control group. To give the experimental group the Huangqi Jianzhong decoction minus the jujube flavored yam, tuckahoe;Control group was given omeprazole treatment, and follow-up record for side effects. Results:The efficiency of the experimental group was 96.66%, control group was 63.33%. The difference had statistical significance (P<0.05);Experimental group appeared side effects for a total of 1 case, the control group in a total of 9 cases. There was no statistically significant difference (P>0.05). Conclusion:The Huangqi Jianzhong decoction decreases peptic ulcer with obvious therapeutic effect. The side effect is fewer, can reduce long-term recurrence rate. The clinical curative effect is worthy of recognition.