中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2013年
18期
15-16
,共2页
王巨超%孙成晖%刘红梅%严伟红
王巨超%孫成暉%劉紅梅%嚴偉紅
왕거초%손성휘%류홍매%엄위홍
ER(+)%PR(+)绝经前乳腺癌%放化疗后%子宫内膜%中医临床特点
ER(+)%PR(+)絕經前乳腺癌%放化療後%子宮內膜%中醫臨床特點
ER(+)%PR(+)절경전유선암%방화료후%자궁내막%중의림상특점
ER(+),PR(+) premenopausal breast cancer%Chemotherapy%Endometrium%Clinical characteristics of TCM
目的：探讨中药自拟方调和饮对绝经前经手术放化疗后口服内分泌药物三苯氧胺的乳腺癌患者子宫内膜的影响，为临床提供资料。方法：选取2011年1月～2011年12月期间，黑龙江中医药大学附属二院肿瘤科符合纳入及排除标准的乳腺癌患者60例。选取住院天数、中医临床症状、辅助检查结果等相对完整的患者随机分为对照组（只口服他莫昔芬），治疗组（口服他莫昔芬同时口服调和饮）各30例，并就收集的资料进行统计分析。结果：①治疗组治疗前子宫内膜厚度为（4.13±1.55），治疗后子宫内膜为（5.83±2.32），与治疗前相比有显著性差异（P<0.01）。②治疗后两组子宫内膜的比较治疗组为（5.83±2.32），对照组为（8.70±2.87），经统计学分析有显著性差异（P<0.01）。结论：调和饮对于绝经前手术放化疗后乳腺癌口服他莫昔芬所致子宫内膜的变化经统计学分析有明显改善作用。
目的：探討中藥自擬方調和飲對絕經前經手術放化療後口服內分泌藥物三苯氧胺的乳腺癌患者子宮內膜的影響，為臨床提供資料。方法：選取2011年1月～2011年12月期間，黑龍江中醫藥大學附屬二院腫瘤科符閤納入及排除標準的乳腺癌患者60例。選取住院天數、中醫臨床癥狀、輔助檢查結果等相對完整的患者隨機分為對照組（隻口服他莫昔芬），治療組（口服他莫昔芬同時口服調和飲）各30例，併就收集的資料進行統計分析。結果：①治療組治療前子宮內膜厚度為（4.13±1.55），治療後子宮內膜為（5.83±2.32），與治療前相比有顯著性差異（P<0.01）。②治療後兩組子宮內膜的比較治療組為（5.83±2.32），對照組為（8.70±2.87），經統計學分析有顯著性差異（P<0.01）。結論：調和飲對于絕經前手術放化療後乳腺癌口服他莫昔芬所緻子宮內膜的變化經統計學分析有明顯改善作用。
목적：탐토중약자의방조화음대절경전경수술방화료후구복내분비약물삼분양알적유선암환자자궁내막적영향，위림상제공자료。방법：선취2011년1월～2011년12월기간，흑룡강중의약대학부속이원종류과부합납입급배제표준적유선암환자60례。선취주원천수、중의림상증상、보조검사결과등상대완정적환자수궤분위대조조（지구복타막석분），치료조（구복타막석분동시구복조화음）각30례，병취수집적자료진행통계분석。결과：①치료조치료전자궁내막후도위（4.13±1.55），치료후자궁내막위（5.83±2.32），여치료전상비유현저성차이（P<0.01）。②치료후량조자궁내막적비교치료조위（5.83±2.32），대조조위（8.70±2.87），경통계학분석유현저성차이（P<0.01）。결론：조화음대우절경전수술방화료후유선암구복타막석분소치자궁내막적변화경통계학분석유명현개선작용。
Objective: To investigate the effect in treating chemotherapy after operation of oral endocrine medicine tamoxifen uterine endometrium in patients with breast cancer by TCM self-made decoction, to provide data for clinical. Methods:From 2011 January to 2011 December in Department of oncology, the second affiliated hospital of heilongjiang university of Chinese Medicine in line with the 60 cases of breast cancer patients into and exclusion standard, select the days of hospitalization, clinical symptoms, the results of auxiliary examinations were randomly divided into control group (only oral tamoxifen), the treatment group (oral tamoxifen and oral mixed drink) with 30 cases in each, Statistical analysis were made based on data. Results: ①The treatment group before treatment, endometrial thickness was (4.13±1.55), after treatment of endometrium was (5.83±2.32), there was significant difference compared with before treatment (P<0.01). ②After the treatment of two groups of endometrial comparison of treatment group was (5.83±2.32), control group was (8.70±2.87), statistically significant differences (P<0.01). Conclusion:Tiaohe decoction was effective on treating chemotherapy after operation of oral endocrine medicine tamoxifen uterine endometrium in patients with breast cancer.
