中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2013年
18期
7-9
,共3页
田风胜%苏秀海%王元松%王晓蕴%李文东%张忠勇%郭瑞卿%韩中千%吕树泉%迟秀娥
田風勝%囌秀海%王元鬆%王曉蘊%李文東%張忠勇%郭瑞卿%韓中韆%呂樹泉%遲秀娥
전풍성%소수해%왕원송%왕효온%리문동%장충용%곽서경%한중천%려수천%지수아
三黄益肾胶囊%糖尿病肾病%24h尿微量白蛋白定量%总症候积分
三黃益腎膠囊%糖尿病腎病%24h尿微量白蛋白定量%總癥候積分
삼황익신효낭%당뇨병신병%24h뇨미량백단백정량%총증후적분
Sanhuang Yishen capsule%Diabetic nephropathy%24h urine albumin%Total symptom scores
目的：探讨三黄益肾胶囊治疗早期糖尿病肾病的临床疗效。方法：所有患者分为洛丁新组、洛丁新＋三黄益肾组和三黄益肾组，三组分别给予相应治疗。3个月后，测定24h 尿微量白蛋白及总症候积分等的变化，并进行比较。结果：①各组治疗后较治疗前，除洛丁新组24h 尿微量白蛋白无明显变化外（P>0.05）、其余两组均明显改善（P<0.05）；总症候积分均明显改善（P<0.05）。②三组治疗后组间比较：24h 尿微量白蛋白，洛丁新＋三黄益肾组，明显优于三黄益肾组及洛丁新组（P<0.05），三黄益肾组与洛丁新组比较无明显差异（P>0.05）。总症候积分，洛丁新＋三黄益肾组与三黄益肾组，明显优于洛丁新组（P<0.05），三黄益肾组与洛丁新＋三黄益肾组比较无明显差异（P>0.05）。结论：三黄益肾胶囊能明显减少早期糖尿病肾病患者的尿微量白蛋白的漏出，同时能明显改善患者症候积分。
目的：探討三黃益腎膠囊治療早期糖尿病腎病的臨床療效。方法：所有患者分為洛丁新組、洛丁新＋三黃益腎組和三黃益腎組，三組分彆給予相應治療。3箇月後，測定24h 尿微量白蛋白及總癥候積分等的變化，併進行比較。結果：①各組治療後較治療前，除洛丁新組24h 尿微量白蛋白無明顯變化外（P>0.05）、其餘兩組均明顯改善（P<0.05）；總癥候積分均明顯改善（P<0.05）。②三組治療後組間比較：24h 尿微量白蛋白，洛丁新＋三黃益腎組，明顯優于三黃益腎組及洛丁新組（P<0.05），三黃益腎組與洛丁新組比較無明顯差異（P>0.05）。總癥候積分，洛丁新＋三黃益腎組與三黃益腎組，明顯優于洛丁新組（P<0.05），三黃益腎組與洛丁新＋三黃益腎組比較無明顯差異（P>0.05）。結論：三黃益腎膠囊能明顯減少早期糖尿病腎病患者的尿微量白蛋白的漏齣，同時能明顯改善患者癥候積分。
목적：탐토삼황익신효낭치료조기당뇨병신병적림상료효。방법：소유환자분위락정신조、락정신＋삼황익신조화삼황익신조，삼조분별급여상응치료。3개월후，측정24h 뇨미량백단백급총증후적분등적변화，병진행비교。결과：①각조치료후교치료전，제락정신조24h 뇨미량백단백무명현변화외（P>0.05）、기여량조균명현개선（P<0.05）；총증후적분균명현개선（P<0.05）。②삼조치료후조간비교：24h 뇨미량백단백，락정신＋삼황익신조，명현우우삼황익신조급락정신조（P<0.05），삼황익신조여락정신조비교무명현차이（P>0.05）。총증후적분，락정신＋삼황익신조여삼황익신조，명현우우락정신조（P<0.05），삼황익신조여락정신＋삼황익신조비교무명현차이（P>0.05）。결론：삼황익신효낭능명현감소조기당뇨병신병환자적뇨미량백단백적루출，동시능명현개선환자증후적분。
Objective:To discuss the effect of the Sanhuang Yishen capsule on treating early diabetic nephropathy. Methods:All the patients were divided into the Lotensin group, the Lotensin plus Sanhuang Yishen group and the Sanhuang Yishen group. After 3 months, measure and compare the 24h urine albumin and total symptom scores and other changes. Results: Lotensin group had no significant changes in 24h urine albumin after treatment than before treatment (P>0.05). The other two groups were significantly improved (P<0.05);total symptom scores were significantly improved (P<0.05). To compare three groups after treatment between every two groups:24-hour urine albumin, Lotensin+Sanhuang Yishen group, was significantly better than the Sanhuang Yishen group and Lotensin group (P<0.05), Sanhuang Yishen group and Lotensin group showed no significant difference (P>0.05). Total symptom scores, Lotensin+Sanhuang Yishen group and Sanhuang Yishen group were much better than Lotensin group (P<0.05), Sanhuang Yishen group and Lotensin+Sanhuang Yishen group showed no significant difference (P>0.05). Conclusion:The Sanhuang Yishen capsule can significantly reduce the leakage of urine albumin in patients with early diabetic nephropathy, and can significantly improve symptom scores.
