CAJ | 학술논문

目的：观察地西泮联合小剂量阿立哌唑治疗酒依赖患者的临床效果。方法将144例酒依赖患者随机分为治疗组和对照组各72例。2组均接受常规治疗，治疗组在常规治疗基础上加服阿立哌唑治疗，对比2组治疗前后戒断症状评分。结果2组治疗前戒断症状评分差异无统计学意义（P＞0．05）。治疗后2组戒断症状评分均低于治疗前，且观察组低于对照组，差异均有统计学意义（P＜0．05）。结论地西泮联合小剂量阿立哌唑治疗酒依赖患者疗效较好，且起效时间短，不良反应轻微，值得推广应用。
목적：관찰지서반연합소제량아립고서치료주의뢰환자적림상효과。방법장144례주의뢰환자수궤분위치료조화대조조각72례。2조균접수상규치료，치료조재상규치료기출상가복아립고서치료，대비2조치료전후계단증상평분。결과2조치료전계단증상평분차이무통계학의의（P＞0．05）。치료후2조계단증상평분균저우치료전，차관찰조저우대조조，차이균유통계학의의（P＜0．05）。결론지서반연합소제량아립고서치료주의뢰환자료효교호，차기효시간단，불량반응경미，치득추엄응용。
Objective To observe the clinical efficacy of diazepam combined with aripiprazole in patients with alcohol dependence .Methods 144 cases patients with alcohol dependence were divided into treatment group and control group ,each of 72 cases.The 2 groups were treated by conventional treatment .Treatment group,on the basis of conventional treatment ,was treated by diazepam combined with aripiprazole .After treatment,compared the withdrawal symptoms score of 2 groups.Results Before treatment,the withdrawal symptoms score of 2 groups was no statistically significant (P>0.05).After treatment,the with-drawal symptoms score of 2 groups were less than that of control group ,and the withdrawal symptoms score of treatment group was less than that of control group ,the difference was statistically significant ( P<0.05) .Conclusion Diazepam combined with arip-iprazole in patients with alcohol dependence has an good efficacy ,less adverse reactions ,and worthy of application .