中国现代药物应用
中國現代藥物應用
중국현대약물응용
CHINESE JOURNAL OF MODERN DRUG APPLICATION
2014年
10期
94-96
,共3页
血药浓度监测%抗癫痫药物%分析
血藥濃度鑑測%抗癲癇藥物%分析
혈약농도감측%항전간약물%분석
Serum concentrations monitoring%Anti-epilepsy drugs%Analysis
目的：评价治疗药物监测对临床治疗的指导作用。方法分析227例服用抗癫痫药物患者的血药浓度监测结果。结果共监测4种抗癫痫药物，其中卡马西平血药浓度在推荐浓度范围内的比例最高，苯妥英钠偏离推荐浓度的比例最高。结论抗癫痫药物血药浓度个体差异较大，影响因素较多，应结合其他临床指标综合分析监测结果。
目的：評價治療藥物鑑測對臨床治療的指導作用。方法分析227例服用抗癲癇藥物患者的血藥濃度鑑測結果。結果共鑑測4種抗癲癇藥物，其中卡馬西平血藥濃度在推薦濃度範圍內的比例最高，苯妥英鈉偏離推薦濃度的比例最高。結論抗癲癇藥物血藥濃度箇體差異較大，影響因素較多，應結閤其他臨床指標綜閤分析鑑測結果。
목적：평개치료약물감측대림상치료적지도작용。방법분석227례복용항전간약물환자적혈약농도감측결과。결과공감측4충항전간약물，기중잡마서평혈약농도재추천농도범위내적비례최고，분타영납편리추천농도적비례최고。결론항전간약물혈약농도개체차이교대，영향인소교다，응결합기타림상지표종합분석감측결과。
Objective To evaluate the guidelines of therapeutic drug monitoring in clinic. Methods The serum concentration of 227 cases were analyzed. Results Four kinds of anti-epilepsy drugs were detected. Carbamazepine was the highest proportion in the effective range, while phenytoin was the highest proportion of deviation from the recommended range. Conclusion The effective concentration of anti-epilepsy drugs varied in different patients and many factors were included. So different indications should be combined to evaluate the efficacy of anti-epilepsy drugs.
