中国中西医结合急救杂志
中國中西醫結閤急救雜誌
중국중서의결합급구잡지
INTEGRATED TRADITIONAL CHINESE AND WESTERN MEDICINE IN PRACTICE OF CRITICAL CARE MEDICINE
2014年
3期
219-221
,共3页
反流性食管炎%老年%生存质量%健康调查简易量表
反流性食管炎%老年%生存質量%健康調查簡易量錶
반류성식관염%노년%생존질량%건강조사간역량표
Reflux esophagitis%Aged patients%Quality of life%The MOS 36-item short form healthy survey
目的：观察疏肝和胃法对老年反流性食管炎患者生存质量的影响，评价中医药治疗慢性疾病的疗效。方法选择2012年3月至2013年10月河南省中医院门诊和住院的反流性食管炎老年患者60例，按随机数字表法分为对照组与试验组，每组30例。对照组给予单纯西药治疗，试验组给予逍遥散加减联合奥美拉唑及吗丁啉治疗，治疗8周。用健康调查简易量表（SF-36量表）评价患者生存质量的改善程度，观察两组临床疗效及不良反应发生情况。结果两组经治疗后，SF-36量表总评分、躯体健康评分（PCS）及精神健康评分（MCS）均明显升高，且以试验组升高程度更显著〔量表总评分（分）：124.2±11.5比117.1±10.9，PCS（分）：67.9±5.3比62.9±6.2，MCS（分）：56.1±6.7比55.0±6.6，均P＜0.05〕；试验组总有效率明显高于对照组（96.7%比80.0%，P＜0.05）。两组均未见明显不良反应发生。结论疏肝和胃法可改善老年反流性食管炎患者的生存质量。
目的：觀察疏肝和胃法對老年反流性食管炎患者生存質量的影響，評價中醫藥治療慢性疾病的療效。方法選擇2012年3月至2013年10月河南省中醫院門診和住院的反流性食管炎老年患者60例，按隨機數字錶法分為對照組與試驗組，每組30例。對照組給予單純西藥治療，試驗組給予逍遙散加減聯閤奧美拉唑及嗎丁啉治療，治療8週。用健康調查簡易量錶（SF-36量錶）評價患者生存質量的改善程度，觀察兩組臨床療效及不良反應髮生情況。結果兩組經治療後，SF-36量錶總評分、軀體健康評分（PCS）及精神健康評分（MCS）均明顯升高，且以試驗組升高程度更顯著〔量錶總評分（分）：124.2±11.5比117.1±10.9，PCS（分）：67.9±5.3比62.9±6.2，MCS（分）：56.1±6.7比55.0±6.6，均P＜0.05〕；試驗組總有效率明顯高于對照組（96.7%比80.0%，P＜0.05）。兩組均未見明顯不良反應髮生。結論疏肝和胃法可改善老年反流性食管炎患者的生存質量。
목적：관찰소간화위법대노년반류성식관염환자생존질량적영향，평개중의약치료만성질병적료효。방법선택2012년3월지2013년10월하남성중의원문진화주원적반류성식관염노년환자60례，안수궤수자표법분위대조조여시험조，매조30례。대조조급여단순서약치료，시험조급여소요산가감연합오미랍서급마정람치료，치료8주。용건강조사간역량표（SF-36량표）평개환자생존질량적개선정도，관찰량조림상료효급불량반응발생정황。결과량조경치료후，SF-36량표총평분、구체건강평분（PCS）급정신건강평분（MCS）균명현승고，차이시험조승고정도경현저〔량표총평분（분）：124.2±11.5비117.1±10.9，PCS（분）：67.9±5.3비62.9±6.2，MCS（분）：56.1±6.7비55.0±6.6，균P＜0.05〕；시험조총유효솔명현고우대조조（96.7%비80.0%，P＜0.05）。량조균미견명현불량반응발생。결론소간화위법가개선노년반류성식관염환자적생존질량。
Objective To observe the effects of liver-discharging and stomach-harmonizing therapy on quality of life in senile patients with reflux esophagitis and to evaluate the therapeutic effect of traditional Chinese medicine (TCM) on chronic diseases. Methods Sixty patients with senile reflux esophagitis selected from in-patients and out-patients of Henan Province Hospital of TCM from March 2012 to October 2013 were randomly divided into experimental group and control group(each,30 patients). The experimental group was treated with Xiaoyao powder (its ingredients could be added or subtracted according to the patient's individual situation)combined with omeprazole and domperidone,while in the control group,only western drugs,omeprazole and domperidone were applied. The therapies in both groups lasting for 8 weeks constituted one therapeutic course. The MOS 36-item short form healthy survey(SF-36)was used to evaluate the degree of improvement of patients,quality of life,and clinical effects and adverse drug reaction were observed. Results The total scores of SF-36,physical and mental health scores of both groups were increased significantly,and the degree of elevation in scores in the experimental group was markedly higher than that in the control group(total scores of SF-36:124.2±11.5 vs. 117.1±10.9,physical health scores:67.9±5.3 vs. 62.9±6.2,mental health scores:56.1±6.7 vs. 55.0±6.6,all P<0.05). The total effective rate of experimental group was much superior to that of control group(96.7%vs. 80.0%,P<0.05). No obvious adverse reactions happened in the two groups. Conclusion Liver-discharging and stomach-harmonizing therapy can improve the quality of life in aged patients with reflux esophagitis.
