CAJ | 학술논문

目的：观察顺铂联合平阳霉素在舌癌患者术前诱导化疗中的应用效果。方法选取高州市人民医院收治的40例需手术治疗的舌癌患者，随机分为2组（n=20）。联合用药组患者术前诱导化疗时应用顺铂+平阳霉素，单一用药组则单用平阳霉素。记录2组患者肿瘤缓解情况和不良反应。结果联合用药组术前诱导化疗的效果比单一用药组好，差异有统计学意义（P＜0.05）；2组不良反应比较，差异无统计学意义。结论对舌癌患者行术前诱导化疗，顺铂联合平阳霉素效果更好，副作用少，值得临床推广应用。
목적：관찰순박연합평양매소재설암환자술전유도화료중적응용효과。방법선취고주시인민의원수치적40례수수술치료적설암환자，수궤분위2조（n=20）。연합용약조환자술전유도화료시응용순박+평양매소，단일용약조칙단용평양매소。기록2조환자종류완해정황화불량반응。결과연합용약조술전유도화료적효과비단일용약조호，차이유통계학의의（P＜0.05）；2조불량반응비교，차이무통계학의의。결론대설암환자행술전유도화료，순박연합평양매소효과경호，부작용소，치득림상추엄응용。
Objective To observe the effect of cisplatin combined with pingyangmycin for preoperative inductive chemotherapy on the patients underwent tongue cancer. Methods Forty tongue cancer patients underwent operation were divided into two groups. combined medicine group and simple medicine group.The patients in the combined medicine group were administrated with cisplatin and pingyangmycin for preoperative inductive chemotherapy. The patients in the simple medicine group were administrated with pingyangmycin for preoperative inductive chemotherapy.The chemotherapeutic efficacy and complication in both groups were recorded. Results The chemotherapeutic efficacy in the combined medicine group was better than it in the simple medicine group.The complication were not significantly different between two groups. Conclusion Cisplatin combined with pingyangmycin for preoperative inductive chemotherapy are effective for the patients underwent tongue cancer and the complication are few.