CAJ | 학술논문

目的：探讨冠心病主要危险因素及相应理化指标与血瘀证的相关性。方法采用横断面研究设计,入选2011年3月-2011年7月阜外心血管病医院、安贞医院、中日友好医院及中国中医科学院西苑医院4家医院就诊的冠心病血瘀证和非血瘀证患者共319例。观察并记录四诊信息及实验室检查结果,采用二分类非条件Logistic回归及多元相关分析,探讨各因素与冠心病血瘀证的相关性。结果 Logistic回归分析显示：高血压(OR=3.942,P=0.000)、血脂异常(OR=3.054,P=0.000)、糖尿病(OR=1.871,P=0.032)、吸烟(OR=1.831,P=0.042)是血瘀证的相关因素；总胆固醇(OR=2.109,P=0.038)、低密度脂蛋白胆固醇(OR=1.598,P=0.039)、收缩压(OR=1.022,P=0.026)、吸烟量(OR=1.001,P=0.001)是冠心病血瘀证的相关临床指标；多元相关分析显示：吸烟量(r=0.282,P=0.000)、收缩压(r=0.120,P=0.033)和低密度脂蛋白胆固醇(r=0.118,P=0.036)与血瘀证计分呈正相关。结论高血压、血脂异常、糖尿病和吸烟是冠心病和血瘀证共同相关的危险因素,总胆固醇、低密度脂蛋白胆固醇、收缩压和吸烟是冠心病和血瘀证共同相关的临床指标,低密度脂蛋白胆固醇、收缩压和吸烟与血瘀证计分呈正相关。
목적：탐토관심병주요위험인소급상응이화지표여혈어증적상관성。방법채용횡단면연구설계,입선2011년3월-2011년7월부외심혈관병의원、안정의원、중일우호의원급중국중의과학원서원의원4가의원취진적관심병혈어증화비혈어증환자공319례。관찰병기록사진신식급실험실검사결과,채용이분류비조건Logistic회귀급다원상관분석,탐토각인소여관심병혈어증적상관성。결과 Logistic회귀분석현시：고혈압(OR=3.942,P=0.000)、혈지이상(OR=3.054,P=0.000)、당뇨병(OR=1.871,P=0.032)、흡연(OR=1.831,P=0.042)시혈어증적상관인소；총담고순(OR=2.109,P=0.038)、저밀도지단백담고순(OR=1.598,P=0.039)、수축압(OR=1.022,P=0.026)、흡연량(OR=1.001,P=0.001)시관심병혈어증적상관림상지표；다원상관분석현시：흡연량(r=0.282,P=0.000)、수축압(r=0.120,P=0.033)화저밀도지단백담고순(r=0.118,P=0.036)여혈어증계분정정상관。결론고혈압、혈지이상、당뇨병화흡연시관심병화혈어증공동상관적위험인소,총담고순、저밀도지단백담고순、수축압화흡연시관심병화혈어증공동상관적림상지표,저밀도지단백담고순、수축압화흡연여혈어증계분정정상관。
Objective To explore the correlation between blood stasis syndrome (BSS)and main risk factors as well as relevant physical and chemical indicators in patients with coronary artery disease (CAD).Methods A total of 3 1 9 patients were divided into coronary heart disease blood stasis syndrome (CAD BSS)group and coronary heart disease non blood stasis syndrome (CAD non-BSS)group.Through cross sectional survey method,clinical data were collected in detail.The correlation between factors in different categories and BSS was analyzed by binary unconditional Logistic regression analysis and multivariate correlation analysis.Results Hypertension (OR=3.942,P=0.000),dyslipidemia (OR=3.054,P=0.000),diabetes mellitus (OR=1.871,P=0.032),and smok-ing (OR=1.831,P=0.042)were relevant factors for BSS.Total cholesterol (OR=2.109,P=0.038),low density lipoprotein cho-lesterol (OR=1.598,P=0.039),systolic blood pressure (OR=1.022,P=0.026),and the number of cigarettes smoked (OR=1.001,P=0.001)were relevant clinical indicators of CAD BSS.Low density lipoprotein cholesterol,systolic blood pressure,and the number of cigarettes smoked were positively related to BSS score.Conclusion There were common risk factors and clinical indicators in CAD and BSS.Some of clinical indicators were positively related to BSS score.