CAJ | 학술논문

目的研究早产儿体液免疫功能变化，探讨早产儿体液免疫功能低下的病因。方法收集246例早产儿组和30例健康新生儿（健康对照组）静脉血标本3 mL ，采用全自动生化分析仪检测各组新生儿IgG、IgM、IgA和补体C3、C4水平。结果
목적연구조산인체액면역공능변화，탐토조산인체액면역공능저하적병인。방법수집246례조산인조화30례건강신생인（건강대조조）정맥혈표본3 mL ，채용전자동생화분석의검측각조신생인IgG、IgM、IgA화보체C3、C4수평。결과
Objective To study changes of humoral immunity of the premature infants in different pathological conditions and detect the reason of the deficiency of humoral immunity in premature infants .Methods Two hundred and forty-six prematur were enrolled and 30 healthy neonates were selected as control group .The percentages of IgG ,IgA ,IgM and comp lement C3 ,C4 were detected by full automatic biochemical analyzer .Results The results showed that IgG ,IgM ,IgA ,C3 and C4 in the premature in-fants were lower than those in the normal term infants and there was a highly significant difference with the decrease of fetal age . IgG ,IgM ,IgA ,C3 and C4 of the group of the premature infants ranging from 32 to 36 weeks had reduced in different degree ,rela-tive to the groups of BW <2 000 g ,hypertension during pregnancy ,cesarean section(P<0 .05) .Conclusion The results showed that function of humoral immunity in the premature infants was depressed and low gestational age ,low birth weight ,cesarean sec-tion and hypertension during pregnancy may be the leading cause of the deficiency of humoral immunity .