CAJ | 학술논문

目的探讨心脏再同步化治疗（CRT）对慢性心力衰竭的临床疗效。方法46例慢性心力衰竭患者行双心室再同步化起搏治疗。术后随访30±5个月，观察患者的NYHA心功能分级,QRS时限,左心室射血分数（LVEF）,左心室舒张末内径（LVDd）的变化。结果46例患者顺利完成CRT植入术,46例患者NYHA心功能分级由术前4级改善为1-2级, QRS时限由术151.0±11.5ms减少到120.2±3.7ms,左心室射血分数由术前0.29±0.04增加到0.49±0.07；左心室舒张末内径由术前70.9±8.4mm减少到52.0±6.8mm, P<0.01。结论 CRT结合药物治疗可显著改善慢性心力衰竭患者的心功能和临床症状,提高患者的生活质量。
목적탐토심장재동보화치료（CRT）대만성심력쇠갈적림상료효。방법46례만성심력쇠갈환자행쌍심실재동보화기박치료。술후수방30±5개월，관찰환자적NYHA심공능분급,QRS시한,좌심실사혈분수（LVEF）,좌심실서장말내경（LVDd）적변화。결과46례환자순리완성CRT식입술,46례환자NYHA심공능분급유술전4급개선위1-2급, QRS시한유술151.0±11.5ms감소도120.2±3.7ms,좌심실사혈분수유술전0.29±0.04증가도0.49±0.07；좌심실서장말내경유술전70.9±8.4mm감소도52.0±6.8mm, P<0.01。결론 CRT결합약물치료가현저개선만성심력쇠갈환자적심공능화림상증상,제고환자적생활질량。
Objective: To appraise the therapeutic effects of resynchronous biventricular pacing on refractory chronic heart failure.Methods:46 patients with chronic refractory heart failure accompanied by intraventricular conduction delay were selected to receive resynchronous biventricular pacing. Changes of NYHA functional class, QRS duration, left ventricular ejection fraction (LVEF),left ventricular end diastolic diameter(LVEDD) were observed before and after packer implantation. Results: after implantation, NYHA functional class was obviously improved.QRS duration was obviously decreased to 120.2±3.7ms from 151.0±11.5ms. LVEF was obviously increased to 0.49±0.07 from 0.29±0.04. LVEDD was decreased to 52.0±6.8mm from 70.9±8.4mm. Conclusion: Resynchronous biventricular pacing can improve hemodynamics, cardiac function, clinical symptoms and quality of life in patients with chronic refractory heart failure.