CAJ | 학술논문

目的观察依达拉奉联合纤溶酶治疗急性脑梗死的临床疗效。方法将急性脑梗死患者80例随机分为2组：治疗组40例，依达拉奉注射液30 mg加生理盐水100 mL静脉滴注，每日2次，联合纤溶酶注射液首日100 U加5％葡萄糖注射液250 m L静脉滴注，第2天起200 U加5％葡萄糖注射液250 m L静脉滴注，共14 d；对照组40例，单用纤溶酶，剂量及用法同治疗组。治疗前后监测神经功能缺损评分。结果2组治疗后7、14、30、90 d神经功能缺损评分、日常生活活动能力指数治疗组均优于对照组，差异有统计学意义（P＜0．05），治疗前组间差异无统计学意义（P＞0．05）。结论依达拉奉联合纤溶酶治疗急性脑梗死疗效显著。
목적관찰의체랍봉연합섬용매치료급성뇌경사적림상료효。방법장급성뇌경사환자80례수궤분위2조：치료조40례，의체랍봉주사액30 mg가생리염수100 mL정맥적주，매일2차，연합섬용매주사액수일100 U가5％포도당주사액250 m L정맥적주，제2천기200 U가5％포도당주사액250 m L정맥적주，공14 d；대조조40례，단용섬용매，제량급용법동치료조。치료전후감측신경공능결손평분。결과2조치료후7、14、30、90 d신경공능결손평분、일상생활활동능력지수치료조균우우대조조，차이유통계학의의（P＜0．05），치료전조간차이무통계학의의（P＞0．05）。결론의체랍봉연합섬용매치료급성뇌경사료효현저。
Objective To observe the clinical effect of edaravone combined with fibrinolysin for treating acute cerebral infarc-tion .Methods 80 cases of acute cerebral infarction were randomly divided into the two groups .The treatment group(40 cases) was treated by edaravone injection 30mg plus normal saline 100 mL by intravenous drip ,twice daily ,fibrinolysin injection 100 U plus 5%glucose injection 250 mL by intravenous drip on 1 d ,subsequently 200U plus 5% glucose 250 mL by intravenous drip from the next day ,for 14 d;the control group(40 cases ) used fibrinolysin alone ,the dose and usage were same to the treatment group .The neuro-logical impairment scale scores(NIHSS) were monitored before and after treatment in the two groups .Results The NIHSS scores and Barthel index on 7 ,14 ,30 ,90 d after treatment in the treatment group were superior to those in the control group (P<0 .05) ,no statistical difference before treatment between the two group existed .Conclusion Edaravone combined with fibrinolysin has better effect for treating acute cerebral infarction .