中华耳科学杂志
中華耳科學雜誌
중화이과학잡지
CHINESE JOURNAL OF OTOLOGY
2013年
3期
432-434
,共3页
孟令照%吴玮%曾亚伟%郭庆%金真%韩浩伦%王刚%孙建芝%王鸿南%李保卫
孟令照%吳瑋%曾亞偉%郭慶%金真%韓浩倫%王剛%孫建芝%王鴻南%李保衛
맹령조%오위%증아위%곽경%금진%한호륜%왕강%손건지%왕홍남%리보위
内淋巴液%磁共振成像%钆喷酸葡胺%豚鼠
內淋巴液%磁共振成像%釓噴痠葡胺%豚鼠
내림파액%자공진성상%구분산포알%돈서
endolymph%MRI%Gd-DTPA%guinea pig
目的探讨临床用3.0T磁共振成像系统能否在活体豚鼠区分内外淋巴液。方法5只豚鼠在3.0T磁共振下行内耳容积扫描后即刻颈内静脉注射钆喷酸葡胺（3ml/kg)，注射后30分钟、60分钟、90分钟、120分钟、150分钟、180分钟、210分钟、240分钟行内耳容积扫描，观测内耳内外淋巴液成像变化。结果未注射对比剂前仅能显示耳蜗及前庭轮廓，尚不能区分内外淋巴液，注射30分钟后对比剂首先进入前庭及耳蜗底转及蜗顶，注射120分钟见对比剂扩展到全内耳并有较好的显像。结论临床用3.0T磁共振成像可区分豚鼠内外淋巴液，为研究膜迷路积水提供便利。
目的探討臨床用3.0T磁共振成像繫統能否在活體豚鼠區分內外淋巴液。方法5隻豚鼠在3.0T磁共振下行內耳容積掃描後即刻頸內靜脈註射釓噴痠葡胺（3ml/kg)，註射後30分鐘、60分鐘、90分鐘、120分鐘、150分鐘、180分鐘、210分鐘、240分鐘行內耳容積掃描，觀測內耳內外淋巴液成像變化。結果未註射對比劑前僅能顯示耳蝸及前庭輪廓，尚不能區分內外淋巴液，註射30分鐘後對比劑首先進入前庭及耳蝸底轉及蝸頂，註射120分鐘見對比劑擴展到全內耳併有較好的顯像。結論臨床用3.0T磁共振成像可區分豚鼠內外淋巴液，為研究膜迷路積水提供便利。
목적탐토림상용3.0T자공진성상계통능부재활체돈서구분내외림파액。방법5지돈서재3.0T자공진하행내이용적소묘후즉각경내정맥주사구분산포알（3ml/kg)，주사후30분종、60분종、90분종、120분종、150분종、180분종、210분종、240분종행내이용적소묘，관측내이내외림파액성상변화。결과미주사대비제전부능현시이와급전정륜곽，상불능구분내외림파액，주사30분종후대비제수선진입전정급이와저전급와정，주사120분종견대비제확전도전내이병유교호적현상。결론림상용3.0T자공진성상가구분돈서내외림파액，위연구막미로적수제공편리。
Objectives To investigate whether a clinical 3.0T MRI system can distinguish endolymph from perilymph in vivo in guinea pigs. Methods Five guinea pigs were injected with Gd-DTPA via the internal jugular vein (3 ml/kg) at the mo-ment when inner ear volume scans on a 3.0T MRI system were completed. Susequent inner ear volume scans were taken every 30 minutes for 240 min to detect changes of endolymph and perilymph. Results Only outlines of the cochlea and vestibule were visible before Gd-DTPA injection with no distinction between endolymph and perilymph. Uptake of Gd-DTPA firstly oc-curred in the vestibule and the basal turn, and in the apex of cochlea 30 min after the injection. At 120 min after injection, Gd-DTPA uptake was seen throughout the entire inner ear with clear imaging. Conclusions Endolymph of inner ear can be distinguished from the perilymph on a clinical 3.0T MRI system, which may provide great convenience for the study of endo-lymphatic hydrops.
