中国口腔种植学杂志
中國口腔種植學雜誌
중국구강충식학잡지
CHINESE JOURNAL OF ORAL IMPLANTOLOGY
2013年
3期
122-124
,共3页
种植体%支抗%感染%组织学
種植體%支抗%感染%組織學
충식체%지항%감염%조직학
microscrew implant%anchorage%infect%histolog
目的：建立感染微种植体动物模型，观察未加力状态下不同时间段，微螺钉种植体-骨界面各部位的组织变化。方法：健康雄性杂种犬4只，在犬的双侧上颌尖牙近远中、第二双尖牙近远中颊侧骨板各植入微螺钉种植体一只，共16只。微螺钉种植体颈部缠绕正畸橡皮圈及4-0缝合线。分别于术后1周、2周、4周、8周处死动物。 HE染色法观察不同时间段种植体-骨界面的变化。结果：观察期内种植体出现松动、未脱落，1周时种植体周围牙龈粘膜出现明显的红、肿等炎性反应，光镜下出现大量的急慢性炎症细胞，毛细血管增生扩张，有少许新生纤维组织，越接近尖部炎性反应越轻；2周时中部骨质的连续性破坏；4周见颈部少量的骨质破坏，同时有片状的新生骨形成；8周时颈部骨质破坏吸收。结论：国产自攻型微螺钉种植体在感染状态下，骨质的吸收是由颈部向尖部进行的。
目的：建立感染微種植體動物模型，觀察未加力狀態下不同時間段，微螺釘種植體-骨界麵各部位的組織變化。方法：健康雄性雜種犬4隻，在犬的雙側上頜尖牙近遠中、第二雙尖牙近遠中頰側骨闆各植入微螺釘種植體一隻，共16隻。微螺釘種植體頸部纏繞正畸橡皮圈及4-0縫閤線。分彆于術後1週、2週、4週、8週處死動物。 HE染色法觀察不同時間段種植體-骨界麵的變化。結果：觀察期內種植體齣現鬆動、未脫落，1週時種植體週圍牙齦粘膜齣現明顯的紅、腫等炎性反應，光鏡下齣現大量的急慢性炎癥細胞，毛細血管增生擴張，有少許新生纖維組織，越接近尖部炎性反應越輕；2週時中部骨質的連續性破壞；4週見頸部少量的骨質破壞，同時有片狀的新生骨形成；8週時頸部骨質破壞吸收。結論：國產自攻型微螺釘種植體在感染狀態下，骨質的吸收是由頸部嚮尖部進行的。
목적：건립감염미충식체동물모형，관찰미가력상태하불동시간단，미라정충식체-골계면각부위적조직변화。방법：건강웅성잡충견4지，재견적쌍측상합첨아근원중、제이쌍첨아근원중협측골판각식입미라정충식체일지，공16지。미라정충식체경부전요정기상피권급4-0봉합선。분별우술후1주、2주、4주、8주처사동물。 HE염색법관찰불동시간단충식체-골계면적변화。결과：관찰기내충식체출현송동、미탈락，1주시충식체주위아간점막출현명현적홍、종등염성반응，광경하출현대량적급만성염증세포，모세혈관증생확장，유소허신생섬유조직，월접근첨부염성반응월경；2주시중부골질적련속성파배；4주견경부소량적골질파배，동시유편상적신생골형성；8주시경부골질파배흡수。결론：국산자공형미라정충식체재감염상태하，골질적흡수시유경부향첨부진행적。
Objective: The aim of this study was, through the metainfective animal experiment, to observe histological alterations of the different part of the tissue surrounding micro-screw implant for different time (one, two, four, eigth weeks) and to disscuss the healing model of jaw after insertion of microscrew. In the end, hope to give some advice to the clinical operation. Methods: Four male crossbred dogs and sixteen micro-screw implant. There were inserted into by the self-driving microscrew in the upper canines vicinity at cuspidal and molar of crossbred dogs respetively, cotton ligatures and rubber were placed around the healing-abutments to make infect. These dogs were sacrificed at one, two, four, eight weeks in excessive anesthesia respectively. The bone-implant samples were made and were observed under optical microscope after HE stained. Results: Mobility of only two microscrew was observed,but not lost. One weekly, the microscopic features of group were chronic inflammatory changes in the crevices of the implants. Varying degrees of fibrous tissues can be seen. Two weekly, Osteoclasts can been seen with the destruetion of bone. Four weekly, bone destruetion can be seen. Eight wekly, connective tissues can be seen in middle of implants. Conclusion: Micro-screw implants in the infection, bone absorption by the neck to the tip of the microscrew implant.
