CAJ | 학술논문

目的：研究不同浓度的制何首乌水煎浓缩液致小鼠网状内皮系统对血流中惰性炭粒的吞噬廓清能力的影响，探讨制何首乌调整免疫的最佳浓度。方法：以小鼠为实验对象，用2 g/mL（大剂量）、1 g/mL（中剂量）、0．5 g/mL （小剂量）三种不同浓度的制何首乌水煎液给小鼠灌胃12 d ，采用炭粒廓清法来检测RES吞噬异物的能力。结果：大剂量能明显增强RES吞噬功能，中、小剂量组无显著性差异。结论：制何首乌浓度为2g/ml时可显著提高实验小鼠非特异性免疫功能，具有扶正固本的作用。
목적：연구불동농도적제하수오수전농축액치소서망상내피계통대혈류중타성탄립적탄서곽청능력적영향，탐토제하수오조정면역적최가농도。방법：이소서위실험대상，용2 g/mL（대제량）、1 g/mL（중제량）、0．5 g/mL （소제량）삼충불동농도적제하수오수전액급소서관위12 d ，채용탄립곽청법래검측RES탄서이물적능력。결과：대제량능명현증강RES탄서공능，중、소제량조무현저성차이。결론：제하수오농도위2g/ml시가현저제고실험소서비특이성면역공능，구유부정고본적작용。
The paper studied the effect of prepared Radix Polygoni Multiflori decoction concentrated at different concentration on the phagocytic clearance ability of mice to inert carbon particles flow ,exploring the best concentration of prepared Radix Poly-goni Multiflori adjusting immunity .The mouse was taken as the experimental object ,using 2g/ml (high dose) ,1g/ml (middle dose) ,0 .5g/ml (low dose) of three kinds of prepared Radix Polygoni Multiflori decoction of different concentrations of mice for 12 days ,using carbon particle clearance method to detect RES swallowed foreign bodies .The result shows that the high dose group can increase the phagocytic function of RES ,no significant difference in small-and middle dose group .Prepared Ra-dix Polygoni Multiflori (concentration 2g/ml) can significantly improve the non-specific immune function in mice ,with Fuzheng equity role .