CAJ | 학술논문

目的：探讨导致消化性溃疡复发的因素，以求寻找相应的预防措施。方法对本院2011年1月至2013年8月期间收治的160例消化性溃疡住院患者的临床资料进行回顾性分析，定期随访后按是否复发分为复发和未复发两组，进行危险因素分析。结果160例患者中有46例复发，复发率为28.8％。单因素Logistic回归分析发现，吸烟量大、酗酒、春秋季节、幽门螺旋杆菌感染、服用非甾体抗炎药（ NSAIDs）、精神因素、男性是消化性溃疡复发的危险因素；进一步多因素Logistic回归分析显示，吸烟酗酒史、精神因素、NSAIDs服用史、Hp感染是消化性溃疡复发的危险因素。结论吸烟酗酒史、精神因素、NSAIDs、Hp感染是消化性溃疡复发的独立因素，干预这些高危因素可减少溃疡复发。
목적：탐토도치소화성궤양복발적인소，이구심조상응적예방조시。방법대본원2011년1월지2013년8월기간수치적160례소화성궤양주원환자적림상자료진행회고성분석，정기수방후안시부복발분위복발화미복발량조，진행위험인소분석。결과160례환자중유46례복발，복발솔위28.8％。단인소Logistic회귀분석발현，흡연량대、후주、춘추계절、유문라선간균감염、복용비치체항염약（ NSAIDs）、정신인소、남성시소화성궤양복발적위험인소；진일보다인소Logistic회귀분석현시，흡연후주사、정신인소、NSAIDs복용사、Hp감염시소화성궤양복발적위험인소。결론흡연후주사、정신인소、NSAIDs、Hp감염시소화성궤양복발적독립인소，간예저사고위인소가감소궤양복발。
Objective To investigate the relapse factors and its control strategy for peptic ulcer patients .Methods A total of 160 cases of peptic ulcer patients who visited our hospital from Jan 2011 to Aug 2013 was retrospectively analyzed .The recurred pa-tients were assigned as the experimental group , and the others as the control group .The relapse factors for peptic ulcer were observed . Results Among 160 peptic ulcers , there were 46 cases with recurrence with a relapse rate of 28.8%.Single factor logistic regression analysis showed that smoking, drinking, the spring and autumn season, h.pylori (Hp) infection, non-steroid anti-inflammatory drugs (NSAIDs), mental factor, and male were the risk factors for recurrence of peptic ulcer .Further multivariable logistic regression analy-sis showed that smoking, drinking, mental factors, history taking NSAIDs, and Hp infection were also the risk factors for recurrence of peptic ulcer .Conclusions Smoking and alcoholism history , meatal factors , history of taking NSAIDs , and Hp infection were the in-dependent risk factors of recurrence of peptic ulcer , intervention of these risk factor might reduce ulcer recurrence .