微生物学免疫学进展
微生物學免疫學進展
미생물학면역학진전
PROGRESS IN MICROBIOLOGY AND IMMUNOLOGY
2013年
4期
52-54
,共3页
麻疹减毒活疫苗%强化免疫%控制策略
痳疹減毒活疫苗%彊化免疫%控製策略
마진감독활역묘%강화면역%공제책략
Measles attenuated live vaccine%Supplementary immunization activities%Control strategy
目的评价2009年景德镇市麻疹减毒活疫苗强化免疫效果，为消除麻疹提供依据。方法对景德镇市2009年10月麻疹疫苗强化免疫期间的摸底调查、现场接种、评估报告等资料和强化免疫前后的中国疾病预防控制信息系统中麻疹疫情资料进行综合分析。结果强化免疫共接种目标儿童289901剂次，报告接种率为96．69％，快速评估调查接种率为98．38％；强化免疫后人群麻疹抗体阳性率为92．58％、保护率为87．39％。抗体GMT从免疫前的1∶572上升到免疫后的1∶1620，免疫前后人群麻疹抗体GMT差异有统计学意义（t＝4．815，P＜0．0001）。强化免疫后1年景德镇市报告麻疹病例3例，年发病率为0．19/10万，且均为＜8月龄与＞20岁人群，较强化免疫前5年（2004-2008年）的平均发病率（10．44/10万）明显下降，发病率同比下降了98．18％。结论高质量的麻疹减毒活疫苗强化免疫能迅速提高人群的抗体水平，降低麻疹发病率。适时开展强化免疫是加快麻疹控制最安全有效的措施之一。
目的評價2009年景德鎮市痳疹減毒活疫苗彊化免疫效果，為消除痳疹提供依據。方法對景德鎮市2009年10月痳疹疫苗彊化免疫期間的摸底調查、現場接種、評估報告等資料和彊化免疫前後的中國疾病預防控製信息繫統中痳疹疫情資料進行綜閤分析。結果彊化免疫共接種目標兒童289901劑次，報告接種率為96．69％，快速評估調查接種率為98．38％；彊化免疫後人群痳疹抗體暘性率為92．58％、保護率為87．39％。抗體GMT從免疫前的1∶572上升到免疫後的1∶1620，免疫前後人群痳疹抗體GMT差異有統計學意義（t＝4．815，P＜0．0001）。彊化免疫後1年景德鎮市報告痳疹病例3例，年髮病率為0．19/10萬，且均為＜8月齡與＞20歲人群，較彊化免疫前5年（2004-2008年）的平均髮病率（10．44/10萬）明顯下降，髮病率同比下降瞭98．18％。結論高質量的痳疹減毒活疫苗彊化免疫能迅速提高人群的抗體水平，降低痳疹髮病率。適時開展彊化免疫是加快痳疹控製最安全有效的措施之一。
목적평개2009년경덕진시마진감독활역묘강화면역효과，위소제마진제공의거。방법대경덕진시2009년10월마진역묘강화면역기간적모저조사、현장접충、평고보고등자료화강화면역전후적중국질병예방공제신식계통중마진역정자료진행종합분석。결과강화면역공접충목표인동289901제차，보고접충솔위96．69％，쾌속평고조사접충솔위98．38％；강화면역후인군마진항체양성솔위92．58％、보호솔위87．39％。항체GMT종면역전적1∶572상승도면역후적1∶1620，면역전후인군마진항체GMT차이유통계학의의（t＝4．815，P＜0．0001）。강화면역후1년경덕진시보고마진병례3례，년발병솔위0．19/10만，차균위＜8월령여＞20세인군，교강화면역전5년（2004-2008년）적평균발병솔（10．44/10만）명현하강，발병솔동비하강료98．18％。결론고질량적마진감독활역묘강화면역능신속제고인군적항체수평，강저마진발병솔。괄시개전강화면역시가쾌마진공제최안전유효적조시지일。
Objective To evaluate the effectiveness of measles attenuated live vaccine supplementary immunization activi -ties in Jingdezhen in 2009 and provide basis for eliminating measles .Methods Collecting the data of basic investigation , scene vaccination and evaluation reports during measles vaccine supplementary immunization in October 2009 ,the compre-hensive analysis was carried out with the data before and after supplementary immunization which collected from China Dis -ease Prevention and Control Information System .Results This supplementary immunization had inoculation to goal chil-dren 289 901 doses, the reporting inoculation rate was 96.69%,the rapid assessment survey inoculation rate was 98.38%. the measles antibody positive rate was 92.58%, protection rate was 87.39%.GMT antibody was raised from 1 ∶572 to 1 ∶1 620,there was significant difference between before and after immunization (t=4.815,P<0.0001).3 measles cases were reported after supplementary immunization 1 year,the incidence rate was 0.19/100 000 , and the cases were children under 8 years old and people over the age of 20, 5 years before the immunization (2004 to 2008) the average incidence rate (10.44/100 000) , decreased by 98.18%.Conclusions Quality MV SIA can rapidly improve the measles antibody lev-el,decrease incidence rate .Carrying out MV SIA is one of the safe and effective measures to accelerate measles control .
