微生物与感染
微生物與感染
미생물여감염
JOURNAL OF MICROBES AND INFECTION
2013年
3期
166-173
,共8页
皮肤%微生物群落%疾病%高通量测序
皮膚%微生物群落%疾病%高通量測序
피부%미생물군락%질병%고통량측서
Skin%Microbial community%Disease%High-throughput sequencing
皮肤作为人体最大的器官,上面定居着各种各样的微生物,它们大部分是无害的,甚至对人体有益。皮肤表面的生态环境因不同的表面特征和外部因素而呈现不同的格局,使得分布于皮肤上的微生物群落出现差异。分子生物学技术的发展使研究皮肤表面微生物群落的高度多样性和多变性成为可能,而且可从生态系统角度去理解和认识皮肤微生物。本文就皮肤微生物群落的主要特点、微生物群落与疾病的联系及其具体应用等方面作一综述。
皮膚作為人體最大的器官,上麵定居著各種各樣的微生物,它們大部分是無害的,甚至對人體有益。皮膚錶麵的生態環境因不同的錶麵特徵和外部因素而呈現不同的格跼,使得分佈于皮膚上的微生物群落齣現差異。分子生物學技術的髮展使研究皮膚錶麵微生物群落的高度多樣性和多變性成為可能,而且可從生態繫統角度去理解和認識皮膚微生物。本文就皮膚微生物群落的主要特點、微生物群落與疾病的聯繫及其具體應用等方麵作一綜述。
피부작위인체최대적기관,상면정거착각충각양적미생물,타문대부분시무해적,심지대인체유익。피부표면적생태배경인불동적표면특정화외부인소이정현불동적격국,사득분포우피부상적미생물군락출현차이。분자생물학기술적발전사연구피부표면미생물군락적고도다양성화다변성성위가능,이차가종생태계통각도거리해화인식피부미생물。본문취피부미생물군락적주요특점、미생물군락여질병적련계급기구체응용등방면작일종술。
The skin is the largest human organ , inhabited by diverse microorganisms , and most of these microorganisms are harmless or even beneficial to their host .The skin surface is highly variable depending on the characteristics of surface structure and environmental factors ,and this drives the variation of skin microbial communities .The development of molecular methods let us know high diversity and variation of microbial communities in human skins ,and let us understand skin microorganisms with the perception of skin as an ecosystem .The purpose of this review is to describe the patterns of skin microbial community and its association with skin diseases and some related applications .