中国妇幼健康研究
中國婦幼健康研究
중국부유건강연구
CHINESE JOURNAL OF MATERNAL AND CHILD HEALTH RESEARCH
2013年
4期
485-486
,共2页
张美华%张爱东%李娟%李欣迎%邱毅
張美華%張愛東%李娟%李訢迎%邱毅
장미화%장애동%리연%리흔영%구의
身材矮小%儿童%核型分析%异常核型
身材矮小%兒童%覈型分析%異常覈型
신재왜소%인동%핵형분석%이상핵형
short stature%children%karyotype analysis%abnormal chromosome karyotype
目的探讨身材矮小儿童细胞遗传学方面的原因。方法按常规技术方法制备外周血染色体G显带,并进行染色体核型分析。结果在138例受检儿童中,检出染色体异常核型39例,检出率为28.26%;其中常染色体异常1例,性染色体异常38例。结论性染色体异常是儿童身材矮小的重要遗传因素,对身材矮小儿童进行外周血染色体核型分析具有重要意义。
目的探討身材矮小兒童細胞遺傳學方麵的原因。方法按常規技術方法製備外週血染色體G顯帶,併進行染色體覈型分析。結果在138例受檢兒童中,檢齣染色體異常覈型39例,檢齣率為28.26%;其中常染色體異常1例,性染色體異常38例。結論性染色體異常是兒童身材矮小的重要遺傳因素,對身材矮小兒童進行外週血染色體覈型分析具有重要意義。
목적탐토신재왜소인동세포유전학방면적원인。방법안상규기술방법제비외주혈염색체G현대,병진행염색체핵형분석。결과재138례수검인동중,검출염색체이상핵형39례,검출솔위28.26%;기중상염색체이상1례,성염색체이상38례。결론성염색체이상시인동신재왜소적중요유전인소,대신재왜소인동진행외주혈염색체핵형분석구유중요의의。
Objective To explore the chromosome cause of the children with short stature .Methods Peripheral blood chromosome was prepared by conventional techniques , G banding stained and analyzed .Results Of 138 cases with short stature , 39 cases were detected with abnormal chromosome karyotype , accounting for 28.26%.There were 1 case of autosome abnormality and 38 cases of sex chromosome abnormalities .Conclusion Sex chromosome abnormality is an important reason for children with short stature .It is important to take the karyotype analysis of chromosome for children with short stature .