CAJ | 학술논문

如何正确估计两均数比较的优效性临床试验样本量是试验设计阶段的主要研究内容之一。在介绍优效性试验基本概念和样本量估计公式的基础上，通过实例介绍两均数比较的样本量估计，并采用PASS软件演示估计过程，为随机对照临床试验正确估计样本量提供参考。
여하정학고계량균수비교적우효성림상시험양본량시시험설계계단적주요연구내용지일。재개소우효성시험기본개념화양본량고계공식적기출상，통과실례개소량균수비교적양본량고계，병채용PASS연건연시고계과정，위수궤대조림상시험정학고계양본량제공삼고。
Sample size estimation in superiority clinical trials for two means comparison is a key research aspect for clinical trial design .Basic conception and sample size estimation equation about superiority clinical trials were introduced in our research .In addition ,sample size estimation procedures were introduced based on examples and demonstrated by PASS software .A reference was provided for estimating sample size in randomized controlled clinical trial .