CAJ | 학술논문

目的观察替勃龙联合纳米银凝胶治疗老年萎缩性阴道炎的疗效。方法选择老年性萎缩性阴道炎患者136例分为两组，即治疗组为替勃龙联合纳米银凝胶，对照组为替勃龙联合甲硝唑栓，比较两组临床疗效、临床的情况改善、阴道炎症评分和阴道健康状况评分、局部应用不良反应、1年内复发率。结果两组患者临床疗效、治愈率和有效率相仿，无统计学意义（P＞0.05）。治疗后两组患者阴道干燥、性交痛、瘙痒等均消失，而阴道及外阴触痛和阴道及外阴烧灼感治疗组明显优于对照组（P＜0.05）。两组局部应用不良反应有显著性差异，即有统计学意义（P＜0.05）。1年内治疗组复发率低于对照组。结论应用替勃龙联合纳米银凝胶治疗老年萎缩性阴道炎降低了复发率、减轻阴道局部黏膜刺激作用、减少细菌耐药性、疗效显著、安全、经济、方便，值得临床推广应用。
목적관찰체발룡연합납미은응효치료노년위축성음도염적료효。방법선택노년성위축성음도염환자136례분위량조，즉치료조위체발룡연합납미은응효，대조조위체발룡연합갑초서전，비교량조림상료효、림상적정황개선、음도염증평분화음도건강상황평분、국부응용불량반응、1년내복발솔。결과량조환자림상료효、치유솔화유효솔상방，무통계학의의（P＞0.05）。치료후량조환자음도간조、성교통、소양등균소실，이음도급외음촉통화음도급외음소작감치료조명현우우대조조（P＜0.05）。량조국부응용불량반응유현저성차이，즉유통계학의의（P＜0.05）。1년내치료조복발솔저우대조조。결론응용체발룡연합납미은응효치료노년위축성음도염강저료복발솔、감경음도국부점막자격작용、감소세균내약성、료효현저、안전、경제、방편，치득림상추엄응용。
Objective To observe the drug dragon in combination with nano silver gel treatment the curative ef ect of senile atrophic vaginitis. Methods Choose 136 cases of senile atrophic vaginitis patients divided into two groups, the treatment group for drug in combination with nano silver gel, the control for the drug dragon joint metronidazole suppository, compared two groups of clinical curative ef ect and clinical improvement, vaginal inflammation grade and vaginal health, local application of adverse reaction, recurrence in 1 year. Results Two groups of patients with clinical ef icacy and the cure rate and ef ective, no statistical significance (P>0.05). Two group of patients after the treatment of vaginal dryness, painful intercourse, itching, etc al disappear, tenderness and vaginal and vulvar and vaginal and vulvar burning sensation in the treatment group was better than control group (P<0.05). Two groups of local application of adverse reactions are significant dif erence, which was statistical y significant (P<0.05). Treatment group 1 year recurrence rate is lower than the control group. Conclusion Application for drug in combination with nano silver gel to treat senile atrophic vaginitis reduces the recurrence rate, reduce the vaginal mucosa stimulation, reducing bacterial drug resistance, curative effect, safe, economic, convenient, worthy of clinical popularization and application.