CAJ | 학술논문

目的建立颈复康制剂挥发油中苍术素含量的气相色谱(GC)测定方法，并对其在不同介质中的稳定性进行考察。方法采用HP-5(30 m×0.32 mm)石英毛细管柱，氢火焰离子化检测器，程序升温系统，分别于室温和4℃条件下测定20 d内苍术素含量。结果苍术素的线性范围为4.172～41.72μg/mL(r＝0.9997)。苍术油溶液中苍术素的稳定性好于其无水乙醇溶液和颈复康制剂挥发油溶液。结论该方法可用于颈复康制剂挥发油中苍术素的含量测定，低温有助于保持苍术素的稳定性，贮存时间不宜过长。
목적건립경복강제제휘발유중창술소함량적기상색보(GC)측정방법，병대기재불동개질중적은정성진행고찰。방법채용HP-5(30 m×0.32 mm)석영모세관주，경화염리자화검측기，정서승온계통，분별우실온화4℃조건하측정20 d내창술소함량。결과창술소적선성범위위4.172～41.72μg/mL(r＝0.9997)。창술유용액중창술소적은정성호우기무수을순용액화경복강제제휘발유용액。결론해방법가용우경복강제제휘발유중창술소적함량측정，저온유조우보지창술소적은정성，저존시간불의과장。
Objective To establish a method for determination of atractylodin in essential oil of Jingfukang preparations by GC and analyze its stability in different solutions. Methods Using HP-5 quartz capillary column (30 m×0.32 mm), programmed temperature was conducted with the FID as detector. The content of atractylodin was determined both at room temperature and 4 ℃ in 20 days. Results The linear range of atractylodin was 4.172-41.72 μg/mL (r=0.999 7). The stability of atractylodin in essential oil of atractylodes was better than in anhydrous alcohol solution or in essential oil of Jingfukang preparation. Conclusion This method is suitable for the quality control of atractylodin in essential oil of Jingfukang preparations. Low temperature is helpful to the stability of atractylodin. The storage period of essential oil of Jingfukang preparations should not be too long.