中国中医药信息杂志
中國中醫藥信息雜誌
중국중의약신식잡지
CHINESE JOURNAL OF INFORMATION ON TRADITIONAL CHINESE MEDICINE
2013年
7期
21-23,48
,共4页
田景平%吕爱平%郑光%赵静%蔡峰%郭洪涛%展俊平%张弛%姜淼%吕诚
田景平%呂愛平%鄭光%趙靜%蔡峰%郭洪濤%展俊平%張弛%薑淼%呂誠
전경평%려애평%정광%조정%채봉%곽홍도%전준평%장이%강묘%려성
文本挖掘%数据分层算法%流行性乙型脑炎%用药规律
文本挖掘%數據分層算法%流行性乙型腦炎%用藥規律
문본알굴%수거분층산법%류행성을형뇌염%용약규률
text mining technique%data slicing algorithm%epidemic encephalitis B%medication regularity
目的利用文本挖掘技术探索流行性乙型脑炎(简称“乙脑”)临床用药规律。方法检索中国生物医学文献数据库，收集有关乙脑文献数据，采用基于敏感关键词频数统计的数据分层算法，挖掘乙脑中药、中成药、西药及西药与中成药联合应用规律，并利用Cytoscape 2.8软件进行可视化展示。结果中药以生地黄、板蓝根、大青叶、生石膏、黄芩等清热解毒药最为常用；中成药以安宫牛黄丸、清开灵注射液等应用为多；西药以干扰素、利巴韦林等抗病毒药为基础，常常与其他抗病毒药、脑细胞营养药、激素类等药联合应用，这些西药也经常与安宫牛黄丸、清开灵等中成药联合应用。结论文本挖掘能够比较客观地总结疾病用药规律，为临床应用提供参考。
目的利用文本挖掘技術探索流行性乙型腦炎(簡稱“乙腦”)臨床用藥規律。方法檢索中國生物醫學文獻數據庫，收集有關乙腦文獻數據，採用基于敏感關鍵詞頻數統計的數據分層算法，挖掘乙腦中藥、中成藥、西藥及西藥與中成藥聯閤應用規律，併利用Cytoscape 2.8軟件進行可視化展示。結果中藥以生地黃、闆藍根、大青葉、生石膏、黃芩等清熱解毒藥最為常用；中成藥以安宮牛黃汍、清開靈註射液等應用為多；西藥以榦擾素、利巴韋林等抗病毒藥為基礎，常常與其他抗病毒藥、腦細胞營養藥、激素類等藥聯閤應用，這些西藥也經常與安宮牛黃汍、清開靈等中成藥聯閤應用。結論文本挖掘能夠比較客觀地總結疾病用藥規律，為臨床應用提供參攷。
목적이용문본알굴기술탐색류행성을형뇌염(간칭“을뇌”)림상용약규률。방법검색중국생물의학문헌수거고，수집유관을뇌문헌수거，채용기우민감관건사빈수통계적수거분층산법，알굴을뇌중약、중성약、서약급서약여중성약연합응용규률，병이용Cytoscape 2.8연건진행가시화전시。결과중약이생지황、판람근、대청협、생석고、황금등청열해독약최위상용；중성약이안궁우황환、청개령주사액등응용위다；서약이간우소、리파위림등항병독약위기출，상상여기타항병독약、뇌세포영양약、격소류등약연합응용，저사서약야경상여안궁우황환、청개령등중성약연합응용。결논문본알굴능구비교객관지총결질병용약규률，위림상응용제공삼고。
Objective To explore the clinical regularity of drugs on epidemic encephalitis B with text mining technique. Methods The data set on epidemic encephalitis B was downloaded from CBM database. The regularities of Chinese herbal medicine, Chinese patent medicine (CPM), western medicine and the combination of CPM and western medicine on epidemic encephalitis B were mined by data slicing algorithm. The results are showed visually with Cytoscape 2.8 software. Results The main function of herbal pieces was focused on clearing heat and removing toxicity. The herbal pieces such as Rehmanniae Radix Isatidis Raxis, Isatids Folium, Paeoniae Radis rubra and Scutellariae Radix were most often used. Angong Niuhuang Wan and Qingkailing Injection were usually used as CPM. For western medicine, antiviral drugs such as interferon and ribavirin were often used, and they were often used together with brain cells nutrition medicine, hormone, immunopotentiator and so on, and they were also frequently used together with CPM such as Angong Niuhuang Wan and Qingkailing Injection. Conclusion Text mining approach provides an important method in exploring the medication regularity for diseas, and provide refenrence for clinical use.
