CAJ | 학술논문

目的：比较3．0 T磁共振（MRI）动态增强与64层螺旋CT（64-MDCT）多期扫描对肝硬化背景下小肝癌的诊断价值。方法选择肝硬化合并小肝癌患者55例（66个癌性小结节），分别进行3．0 T MRI动态增强与64-MDCT多期扫描，由两位专家对检查结果进行判定，比较两种检查方法的诊断价值。结果两位观察者通过3．0 T MRI动态增强得到的ROC曲线下面积（AUC）分别为0．893±0．013、0．859±0．027，通过64-MDCT得到的AUC分别为0．657±0．034、0．679±0．026；两位观察者对两种检查方法的诊断价值比较，P均＜0．01。两位观察者采用3．0 T MRI动态增强诊断肝硬化背景下小肝癌的敏感度、特异度、阴性预测值均高于64-MDCT，P均＜0．01。结论3．0 T MRI动态增强对肝硬化背景下小肝癌的诊断价值高于64-MDCT。
목적：비교3．0 T자공진（MRI）동태증강여64층라선CT（64-MDCT）다기소묘대간경화배경하소간암적진단개치。방법선택간경화합병소간암환자55례（66개암성소결절），분별진행3．0 T MRI동태증강여64-MDCT다기소묘，유량위전가대검사결과진행판정，비교량충검사방법적진단개치。결과량위관찰자통과3．0 T MRI동태증강득도적ROC곡선하면적（AUC）분별위0．893±0．013、0．859±0．027，통과64-MDCT득도적AUC분별위0．657±0．034、0．679±0．026；량위관찰자대량충검사방법적진단개치비교，P균＜0．01。량위관찰자채용3．0 T MRI동태증강진단간경화배경하소간암적민감도、특이도、음성예측치균고우64-MDCT，P균＜0．01。결론3．0 T MRI동태증강대간경화배경하소간암적진단개치고우64-MDCT。
Objective To evaluate the diagnostic performance of contrast-enhanced 3.0 T magnetic resonance imaging (MRI) and 64-multirow detector CT (64-MDCT) for small hepatocellular carcinoma (HCC) in patients with liver cirrho-sis.Methods Fifty-five cirrhotic patients with small HCCs (66 cancerous nodules ) were admitted to our hospital .All le-sions were quantitatively detected by contrast-enhanced 3.0 T MRI and 64-MDCT scanning.Two observers independently and randomly reviewed the 3.0 T MRI and 64-MDCT images on a lesion-by-lesion basis for the comparison of diagnostic value of the two methods.Results For each observer, the areas under the ROC curve were 0.893 ±0.013 and 0.859 ± 0.027 for 3.0 T MRI, respectively, as opposed to 0.657 ±0.034 and 0.679 ±0.026 for 64-MDCT, respectively.The differences between the two techniques were statistically significant for each observer (all P<0.01).The sensitivity, spe-cificity and negative predictive value of 3.0 T MRI for both observers were significantly higher than those of 64-MDCT ( all P<0.01).Conclusion The contrast-enhanced 3.0 T MRI shows a better diagnostic performance than that of 64-MDCT for the detection of small HCCs in patients with chronic liver disease .