CAJ | 학술논문

目的了解新疆 HIV 感染产妇及其所生婴儿抗艾滋病病毒药物应用状况及变化趋势。方法对预防艾滋病母婴传播管理信息网络直报系统中报告的2010-2012年间分娩的1303例 HIV 感染产妇及其所生婴儿抗病毒药物应用情况进行描述性分析。结果1303例 HIV 感染产妇中，2010-2012年分别有72.58％，77.40％，79.55％的产妇应用了抗病毒药物，并呈逐年上升趋势（χ2＝6.30，P ＜0.05），HIV 感染产妇孕28周及以前开始应用三联方案比例也呈逐年上升趋势（χ2＝13.81，P ＜0.01）；HIV 感染产妇所生婴儿抗逆转录病毒药物应用比例分别为77.63％，84.91％，84.09％，2011年比2010年上升幅度比较明显，2012年比2011年略有下降（χ2＝8.82，P ＜0.01）。结论HIV 感染产妇及所生婴儿抗病毒药物应用比例逐年上升，但仍有较大的上升空间，需要进一步提高 HIV 感染产妇及其所生婴儿抗病毒药物应用比例，从而减少母婴传播的风险。
목적료해신강 HIV 감염산부급기소생영인항애자병병독약물응용상황급변화추세。방법대예방애자병모영전파관리신식망락직보계통중보고적2010-2012년간분면적1303례 HIV 감염산부급기소생영인항병독약물응용정황진행묘술성분석。결과1303례 HIV 감염산부중，2010-2012년분별유72.58％，77.40％，79.55％적산부응용료항병독약물，병정축년상승추세（χ2＝6.30，P ＜0.05），HIV 감염산부잉28주급이전개시응용삼련방안비례야정축년상승추세（χ2＝13.81，P ＜0.01）；HIV 감염산부소생영인항역전록병독약물응용비례분별위77.63％，84.91％，84.09％，2011년비2010년상승폭도비교명현，2012년비2011년략유하강（χ2＝8.82，P ＜0.01）。결론HIV 감염산부급소생영인항병독약물응용비례축년상승，단잉유교대적상승공간，수요진일보제고 HIV 감염산부급기소생영인항병독약물응용비례，종이감소모영전파적풍험。
Objective To understand the anti-HIV drug application status and its trends among HIV-infected mothers and their children in Xinjiang.Methods Reports from Management system of HIV mother-to-child transmission pre-vention network were analyzed from 2010 to 2012,1303 cases of antiviral drugs application among HIV-infected mothers and their Children were carried out descriptive analysis.Results During 2010 -2012,among 1303 HIV positive lying-in women,there was 72.58%,77.40% and 79.55% of them used antiviral drugs with an increased trend by years (χ2 =6.30,P <0.05).There was an upward trend in the ratio of joint solution use beginning among HIV positive pregnant women before the 28th week of gestation (χ2 =13.81,P <0.01).The antiretroviral drugs application proportions among children of HIV-infected pregnant women were 77.63%,84.91%,84.09%,and the obvious increasing in 2011 than in 2010,declined slightly in 2012 than in 2011 (χ2 =8.82,P <0.01).Conclusion Antiviral drugs application proportions among HIV positive pregnant women and their infant increased year by years,but there were still a larger rising space.It is need to further improve antiviral drugs application proportion among them to reduce the risk of mother-to-child transmission.