世界中医药
世界中醫藥
세계중의약
WORLD CHINESE MEDICINE
2013年
8期
871-874,879
,共5页
张会芳%王玲玲%张建斌%姜劲峰
張會芳%王玲玲%張建斌%薑勁峰
장회방%왕령령%장건빈%강경봉
灸温%灸感%高脂血症%氧化低密度脂蛋白%内皮素-1%一氧化氮
灸溫%灸感%高脂血癥%氧化低密度脂蛋白%內皮素-1%一氧化氮
구온%구감%고지혈증%양화저밀도지단백%내피소-1%일양화담
Moxibustion temperature%Moxibustion feeling%Hyperlipidemia%Ox-LDL%ET-1%NO
目的：观察不同灸温对原发性高脂血症患者血脂组分、血清Ox-LDL、ET-1、NO、ET-1/NO的影响，探讨灸法以“温”促“通”效应机制。方法：将42例原发性高脂血症患者随机分为45℃和38℃组，各21例。两组通过调节艾火和穴位皮肤的距离及弹灰的频率控制温度，并用测温仪精确监测皮肤温度。每次每穴治疗10 min，隔日1次，6周为1个疗程，连续治疗2个疗程（12周）后，肘静脉采血10 mL，检测患者血脂7项及血清Ox-LDL、ET-1、NO等指标。结果：45℃组调脂效应明显，降低TC、TG的作用优于38℃组（P＜0.05），45℃组艾灸后高脂血症患者血清Ox-LDL、ET-1、ET-1/NO均明显降低（P＜0.001），45℃艾灸对Ox-LDL、NO、ET-1/NO的调节作用，明显优于38℃。结论：45℃艾灸刺激调脂通脉的作用优于38℃，温度影响艾灸疗效，适宜的温度刺激是艾灸取效的关键因素，TRPV1可能介导艾灸以“温”促“通”效应机制，灼与痛之间的灸感是取效最佳灸感。
目的：觀察不同灸溫對原髮性高脂血癥患者血脂組分、血清Ox-LDL、ET-1、NO、ET-1/NO的影響，探討灸法以“溫”促“通”效應機製。方法：將42例原髮性高脂血癥患者隨機分為45℃和38℃組，各21例。兩組通過調節艾火和穴位皮膚的距離及彈灰的頻率控製溫度，併用測溫儀精確鑑測皮膚溫度。每次每穴治療10 min，隔日1次，6週為1箇療程，連續治療2箇療程（12週）後，肘靜脈採血10 mL，檢測患者血脂7項及血清Ox-LDL、ET-1、NO等指標。結果：45℃組調脂效應明顯，降低TC、TG的作用優于38℃組（P＜0.05），45℃組艾灸後高脂血癥患者血清Ox-LDL、ET-1、ET-1/NO均明顯降低（P＜0.001），45℃艾灸對Ox-LDL、NO、ET-1/NO的調節作用，明顯優于38℃。結論：45℃艾灸刺激調脂通脈的作用優于38℃，溫度影響艾灸療效，適宜的溫度刺激是艾灸取效的關鍵因素，TRPV1可能介導艾灸以“溫”促“通”效應機製，灼與痛之間的灸感是取效最佳灸感。
목적：관찰불동구온대원발성고지혈증환자혈지조분、혈청Ox-LDL、ET-1、NO、ET-1/NO적영향，탐토구법이“온”촉“통”효응궤제。방법：장42례원발성고지혈증환자수궤분위45℃화38℃조，각21례。량조통과조절애화화혈위피부적거리급탄회적빈솔공제온도，병용측온의정학감측피부온도。매차매혈치료10 min，격일1차，6주위1개료정，련속치료2개료정（12주）후，주정맥채혈10 mL，검측환자혈지7항급혈청Ox-LDL、ET-1、NO등지표。결과：45℃조조지효응명현，강저TC、TG적작용우우38℃조（P＜0.05），45℃조애구후고지혈증환자혈청Ox-LDL、ET-1、ET-1/NO균명현강저（P＜0.001），45℃애구대Ox-LDL、NO、ET-1/NO적조절작용，명현우우38℃。결론：45℃애구자격조지통맥적작용우우38℃，온도영향애구료효，괄의적온도자격시애구취효적관건인소，TRPV1가능개도애구이“온”촉“통”효응궤제，작여통지간적구감시취효최가구감。
Objective:To observe the effects of different moxibustion temperature on primary hyperlipidemia patients with serum Ox -LDL, component, ET-1, NO, ET-1/NO, and discuss moxibustion mechanism of promoting “tong” though“wen”.Methods:A tao-tal of 42 cases of primary hyperlipidemia were randomly divided into 45℃group and 38℃group, with 21 cases in each.The tempera-ture of two groups was controled by adjusting the moxibustion distance and the frequency of moving moxibustion ash , and the thermometer accuratly monitor skin temperature .Each point for 10 minutes, once every other day, 6 weeks as 1 course of treatment, totally 2 courses (12 weeks), elbow venous blood 10ml, detect blood fat and serum Ox -LDL, ET-1, NO.Results:45℃group have lipid-lowering effect, the effect is superior to that of TC, TG in 38℃group(P<0.05),the content of Ox-LDL, ET-1, ET-1/NO in serum of pa-tients with hyperlipidemia in 45 ℃group were decreased (P<0.001) after moxibustion.Regulation effect of 45 ℃moxibustion on Ox-LDL, NO, ET-1/NO, was obviously better than 38 ℃.Conclusion: the role of 45 ℃ moxibustion stimulation in “tiao zhi tong mai” was better than 38℃, the temperature of moxibustion can effect clinical effect , the suitable temperature is the key factor of moxi-bustion stimulation effect, TRPV1 may mediate moxibustion mechanism in promoting “tong” effect by“wen”.Moxibustion sensation be-tween burning and pain the is best moxibustion sensation .
