世界中医药
世界中醫藥
세계중의약
WORLD CHINESE MEDICINE
2013年
8期
859-861
,共3页
杨佳%赵百孝%韩丽%刘平%王磊%白桦%黄剑%刘钧天%朱茂祥%杨陟华
楊佳%趙百孝%韓麗%劉平%王磊%白樺%黃劍%劉鈞天%硃茂祥%楊陟華
양가%조백효%한려%류평%왕뢰%백화%황검%류균천%주무상%양척화
不同浓度%艾烟%vWF%ox-LDL%微循环
不同濃度%艾煙%vWF%ox-LDL%微循環
불동농도%애연%vWF%ox-LDL%미순배
Different concentration%Moxa smoke%vWF%ox-LDL%Microcirculation
目的：观察不同浓度艾烟对大鼠血液微循环的影响，为临床安全使用艾烟提供参考。方法：将168只wistar大鼠随机分为四组，每组42只分别暴露于0％、10％、40％、70％浓度（以染毒柜不透光率度量），每天20 min，26周后取材，ELISA法检测不同浓度组大鼠血清中vWF、ox-LDL的含量。结果：vWF含量随艾烟浓度升高而逐渐下降，低、中、高浓度组vWF含量与空白对照组相比均有统计学意义；中浓度组艾烟干预后，血清中ox-LDL含量显著性升高，其余各组ox-LDL含量与空白组相比无统计学意义。结论：1）艾烟可使血小板聚集程度下降，提示艾烟可能具有改善微循环，从而促进机体新陈代谢的作用。2）低浓度艾烟对血管内皮未见明显损伤。
目的：觀察不同濃度艾煙對大鼠血液微循環的影響，為臨床安全使用艾煙提供參攷。方法：將168隻wistar大鼠隨機分為四組，每組42隻分彆暴露于0％、10％、40％、70％濃度（以染毒櫃不透光率度量），每天20 min，26週後取材，ELISA法檢測不同濃度組大鼠血清中vWF、ox-LDL的含量。結果：vWF含量隨艾煙濃度升高而逐漸下降，低、中、高濃度組vWF含量與空白對照組相比均有統計學意義；中濃度組艾煙榦預後，血清中ox-LDL含量顯著性升高，其餘各組ox-LDL含量與空白組相比無統計學意義。結論：1）艾煙可使血小闆聚集程度下降，提示艾煙可能具有改善微循環，從而促進機體新陳代謝的作用。2）低濃度艾煙對血管內皮未見明顯損傷。
목적：관찰불동농도애연대대서혈액미순배적영향，위림상안전사용애연제공삼고。방법：장168지wistar대서수궤분위사조，매조42지분별폭로우0％、10％、40％、70％농도（이염독거불투광솔도량），매천20 min，26주후취재，ELISA법검측불동농도조대서혈청중vWF、ox-LDL적함량。결과：vWF함량수애연농도승고이축점하강，저、중、고농도조vWF함량여공백대조조상비균유통계학의의；중농도조애연간예후，혈청중ox-LDL함량현저성승고，기여각조ox-LDL함량여공백조상비무통계학의의。결론：1）애연가사혈소판취집정도하강，제시애연가능구유개선미순배，종이촉진궤체신진대사적작용。2）저농도애연대혈관내피미견명현손상。
Objective:To observe the effect of moxa somke with different concentrations on blood microcirculation and provide reference on security of moxa smoke in clinic .Methods:A total of 168 rats were randomly divided into 4 groups ,42 in each group.Rats in con-trol group, low concentration goup, medium concentration group , high concentration group were respectively exposed to moxa smoke of 0%, 10%, 40%, 70%concentration (in terms of opacity) for 20 min each day , after 26 weeks rats were executed and drawn materi-als and with ELISA method ox -LDL、vWF in rats blood serum of different group were tested .Results: vWF showed downtrend as the concentration of moxa smoke ascended , which of low, medium, high concenteation group significantly declined compared with control group;It has significantly rise in medium cencentrtion group compared with control group ,the rest groups had no significant change by contrast with control group.Conclusion:1) The rise of concentration of moxa smoke brings down Platelet aggregation ,promotes body metabolism and improves microcirculation .2) Low concentration of moxa smoke indicates no injury on vascular endothelial .
