CAJ | 학술논문

目的探讨重型颅脑损伤患者超早期行肠内营养支持的治疗效果。方法将60例患者按住院单双号分为治疗组和对照组，每组30例，对照组采用常规支持治疗，治疗组于超早期行肠内营养支持治疗，观察比较两组疗效、血生化指标、并发症和预后等情况。结果治疗3周后对患者进行检查，治疗组的体重（BW）、肱三头肌皮皱厚度（TSF）、上臂肌围（AMC）、平衡NB（g/d ）的减少值均大于对照组（P＜0.05），治疗组的血清白蛋白、血红蛋白、血清前白蛋白及格拉斯哥昏迷指数（GOS）评分均高于对照组（P＜0.05），治疗组消化道出血的发生率和病死率均低于对照组（P＜0.01或＜0.05）。结论重型颅脑损伤患者超早期行肠内营养支持可以改善氮平衡，改善患者营养状况，有利于神经功能缺损的康复和骨骼肌的合成，提高机体的免疫力，从而降低消化道出血率和病死率，值得临床推广应用。
목적탐토중형로뇌손상환자초조기행장내영양지지적치료효과。방법장60례환자안주원단쌍호분위치료조화대조조，매조30례，대조조채용상규지지치료，치료조우초조기행장내영양지지치료，관찰비교량조료효、혈생화지표、병발증화예후등정황。결과치료3주후대환자진행검사，치료조적체중（BW）、굉삼두기피추후도（TSF）、상비기위（AMC）、평형NB（g/d ）적감소치균대우대조조（P＜0.05），치료조적혈청백단백、혈홍단백、혈청전백단백급격랍사가혼미지수（GOS）평분균고우대조조（P＜0.05），치료조소화도출혈적발생솔화병사솔균저우대조조（P＜0.01혹＜0.05）。결론중형로뇌손상환자초조기행장내영양지지가이개선담평형，개선환자영양상황，유리우신경공능결손적강복화골격기적합성，제고궤체적면역력，종이강저소화도출혈솔화병사솔，치득림상추엄응용。
Objective To explore the early effect of super early enteral nutrition support in patients with se -vere craniocerebral injury.Methods According to the hospitalized single or double number ,60 patients were divided into treatment group and control group , 30 patients in each group.the control group with was treated conventional therapy.The treatment group received supwer early enteral nutrition support , the efficacy of blood biochemical indica-tors, complications and prognosis were observed and compared .Results At third week after treatment,the dicreased values in body weight(BW), triceps skinfold(TSF), arm muscle circumference(AMC), NB(g/d) in the treatment group were less than those control group (P<0.05).The levels of albumin, hemoglobin serum protein and the GOS scores in the treatment group were higher than those in the control group (P<0.05), the incidence in pulmonary in-fection, abdominal distension, diarrhea, gastrointestinal bleeding and the mortality rates in the treatment group were lower than those in the control group (P<0.01 or P<0.05).Conclusion For patients with severe craniocerebral in -jury,super early enteral nutrition support can promote recovery , improve nitrogen balance and the nutritional status of the patients, help neural function defect rehabilitation and synthesis of skeletal muscle , improve immunity, thereby reducing the pulmonary infection and other complications , reducing the mortality rate.