CAJ | 학술논문

目的探讨在外周神经电刺激引导下A型肉毒毒素(BTX-A)局部注射治疗痉挛型脑瘫的疗效。方法共选取30例痉挛型脑瘫患儿，在外周神经电刺激引导下采用BTX-A局部多点注射，于治疗前、后采用改良Ashworth量表(MAS)和粗大运动功能评定量表(GMFM-88)进行评定。结果 BTX-A注射1周后，MAS评分显著降低，并维持至6个月时(P<0.001)。与治疗前相比，注射1周后，GMFM-88评分无显著性差异(P>0.05)，3个月和6个月时显著增加(P<0.001)。结论外周神经电刺激引导下BTX-A局部多点注射治疗痉挛型脑瘫疗效显著。
목적탐토재외주신경전자격인도하A형육독독소(BTX-A)국부주사치료경련형뇌탄적료효。방법공선취30례경련형뇌탄환인，재외주신경전자격인도하채용BTX-A국부다점주사，우치료전、후채용개량Ashworth량표(MAS)화조대운동공능평정량표(GMFM-88)진행평정。결과 BTX-A주사1주후，MAS평분현저강저，병유지지6개월시(P<0.001)。여치료전상비，주사1주후，GMFM-88평분무현저성차이(P>0.05)，3개월화6개월시현저증가(P<0.001)。결론외주신경전자격인도하BTX-A국부다점주사치료경련형뇌탄료효현저。
Objective To investigate the effects of local injection of Botulinum toxin type A (BTX-A) on spastic cerebral palsy guided by peripheral nerve stimulation. Methods 30 children with spastic cerebral palsy received local multi-point injection of BTX-A guided by peripheral nerve stimulation. They were assessed with modified Ashworth scale (MAS) and Gross Motor Function Assessment Scale (GM-FM-88) before and 1 week, 3 months and 6 months after treatment. Results The scores of MAS decreased significantly 1 week, 3 months and 6 months after treatment (P<0.001). The scores of GMFM-88 increased 3 months and 6 months after treatment (P<0.001). Conclusion Injection of BTX-A guided by peripheral nerve stimulation is effective on spastic cerebral palsy.