CAJ | 학술논문

目的建立补心软脉颗粒的质量控制方法。方法采用薄层色谱法对制剂中的麦冬、山萸肉、水蛭、银杏叶、虎杖进行定性鉴别，采用高效液相色谱法对制剂中红景天苷、马钱苷的含量进行测定。结果薄层色谱能够检出麦冬、山萸肉、水蛭、银杏叶、虎杖。红景天苷在0.2902～2.9024μg范围内线性关系良好，平均回收率(n＝6)为99.64%(RSD＝2.72%)，马钱苷在0.0831～0.8312μg范围内线性关系良好，平均回收率(n＝6)为100.12%(RSD＝2.27%)。结论本方法简便、准确，重复性好，可有效控制补心软脉颗粒的质量。
목적건립보심연맥과립적질량공제방법。방법채용박층색보법대제제중적맥동、산유육、수질、은행협、호장진행정성감별，채용고효액상색보법대제제중홍경천감、마전감적함량진행측정。결과박층색보능구검출맥동、산유육、수질、은행협、호장。홍경천감재0.2902～2.9024μg범위내선성관계량호，평균회수솔(n＝6)위99.64%(RSD＝2.72%)，마전감재0.0831～0.8312μg범위내선성관계량호，평균회수솔(n＝6)위100.12%(RSD＝2.27%)。결론본방법간편、준학，중복성호，가유효공제보심연맥과립적질량。
Objective To establish the quality standard of Buxin Ruanmai granules. Methods TLC was used to identify Ophiopogonis, Corni Fructus, Hirudo, Ginkgo Folium and Polygoni Cuspidati Rhizoma et Radix. HPLC was used to determine the content of salidroside and loganin. Results Ophiopogonis, Corni Fructus, Hirudo, Ginkgo Folium and Polygoni Cuspidati Rhizoma et Radix could be identified by TLC. The linear range of salidroside was within 0.290 2-2.902 4 μg and the average recovery (n=6) was 99.64%(RSD=2.72%). The linear range of loganin was within 0.083 1-0.831 2 μg and the average recovery (n=6) was 100.12% (RSD=2.27%). Conclusion The method is simple, accurate and reproducible, which can effectively control the quality of Buxin Ruanmai granules.