CAJ | 학술논문

目的检测含钛合金和钴铬合金烤瓷熔附金属全冠（ PFM ）修复前后犬龈沟液中肿瘤坏死因子α（ TNF-α）和白细胞介素6（ IL-6）的表达，观察两种非贵金属烤瓷合金的生物学性能。方法将6只犬随机分为两组，分别行含钛合金和钴铬合金PFM修复，分别于修复前、修复后1、2、3个月采集龈沟液，用酶联免疫吸附试验（ELISA）检测其TNF-α和IL-6的表达。结果含钛合金修复后1、3个月，TNF-α的表达有所增加（P＜0．05）。钴铬合金修复前后，TNF-α的表达无明显改变（P＞0．05）。两组修复前后IL-6的表达均无明显改变（P＞0．05）。结论含钛合金较钴铬合金更容易导致牙周组织的炎性改变。
목적검측함태합금화고락합금고자용부금속전관（ PFM ）수복전후견간구액중종류배사인자α（ TNF-α）화백세포개소6（ IL-6）적표체，관찰량충비귀금속고자합금적생물학성능。방법장6지견수궤분위량조，분별행함태합금화고락합금PFM수복，분별우수복전、수복후1、2、3개월채집간구액，용매련면역흡부시험（ELISA）검측기TNF-α화IL-6적표체。결과함태합금수복후1、3개월，TNF-α적표체유소증가（P＜0．05）。고락합금수복전후，TNF-α적표체무명현개변（P＞0．05）。량조수복전후IL-6적표체균무명현개변（P＞0．05）。결론함태합금교고락합금경용역도치아주조직적염성개변。
Objective To investigate the expression of TNF-αand IL-6 in GCF of the dogs after restored with Containing titanium alloy PFM and cobalt -chrome alloy PFM,Observe the biological properties of the two non-precious ceramic alloy.Method six dogs were randomized in two groups.Each of them was restored with containing titanium alloy PFM or cobalt -chrome alloy PFM.Collect the gingival crevicular fluid before restoration and on the 1st,2nd and 3rd month after restoration. The level of TNF-αand IL-6 were detected by ELISA.Result The TNF-αexpression of Containing titanium alloy group was increased(P<0.05)after 1st and 3rd month,and there were no significant changes(P>0.05)in the cobalt-chrome alloy group.There were no significant changes(P>0.05)of the IL-6 expression in the two groups after restoration.Conclusion The containing titanium alloy is more likely to cause inflammatory changes in the periodontal tissues when compared with cobalt-chromium alloy.