中国执业药师
中國執業藥師
중국집업약사
CHINA LICENSED PHARMACIST
2013年
10期
24-26
,共3页
板翘解毒颗粒%薄层色谱法%高效液相色谱法%质量标准
闆翹解毒顆粒%薄層色譜法%高效液相色譜法%質量標準
판교해독과립%박층색보법%고효액상색보법%질량표준
Banqiaojiedu Granules%TLC%HPLC%Quality Standard
目的：研究板翘解毒颗粒的质量标准。方法：采用薄层色谱法（TLC）对板翘解毒颗粒中连翘、板蓝根及知母进行定性鉴别，并建立连翘苷的高效液相色谱法（HPLC）含量测定方法。结果：TLC检出连翘、板蓝根及知母的特征斑点；连翘苷在0.10～4.00μg范围内线性关系良好，平均回收率为99.84%，RSD为2.22%（n=6）。结论：该方法简便、专属性强，可用于该制剂的质量控制。
目的：研究闆翹解毒顆粒的質量標準。方法：採用薄層色譜法（TLC）對闆翹解毒顆粒中連翹、闆藍根及知母進行定性鑒彆，併建立連翹苷的高效液相色譜法（HPLC）含量測定方法。結果：TLC檢齣連翹、闆藍根及知母的特徵斑點；連翹苷在0.10～4.00μg範圍內線性關繫良好，平均迴收率為99.84%，RSD為2.22%（n=6）。結論：該方法簡便、專屬性彊，可用于該製劑的質量控製。
목적：연구판교해독과립적질량표준。방법：채용박층색보법（TLC）대판교해독과립중련교、판람근급지모진행정성감별，병건립련교감적고효액상색보법（HPLC）함량측정방법。결과：TLC검출련교、판람근급지모적특정반점；련교감재0.10～4.00μg범위내선성관계량호，평균회수솔위99.84%，RSD위2.22%（n=6）。결론：해방법간편、전속성강，가용우해제제적질량공제。
Objective: To study the the quality standards of banqiaojiedu granules . Methods: The thin layer chro-matography ( TLC ) method was used in the qualitative identification of fructus forsythiae , radix isatidis and rhizoma anemarrhenae . The content of phillyrin was determined by high performance liquid chromatography ( HPLC ) . Results:Fructus forsythiae, radix isatidis and rhizoma anemarrhenae could be identified by TLC. A good linear relationship was showed at the range of 0 . 10 ~ 4 . 00 μg for phillyrin determination . The average recovery was 99 . 84%, with RSD of 2 . 22% ( n = 6 ) . Conclusion: This method is simple and specific , and could be used for quality control of banqiaojiedu granules .
