中国卒中杂志
中國卒中雜誌
중국졸중잡지
CHINESE JOURNAL OF STROKE
2013年
10期
844-848
,共5页
小脑%组件式结构%小脑功能%认知障碍,血管性
小腦%組件式結構%小腦功能%認知障礙,血管性
소뇌%조건식결구%소뇌공능%인지장애,혈관성
Cerebellum%Modular organization%Cerebellar function%Cognitive impairment,Vascular
小脑不仅与运动有关,而且也参与非运动的认知功能。血管性认知功能障碍是认知功能疾病中的一个重要分支,其主要与脑血管病危险因素及高龄有关。脑组织缺血导致的神经细胞及神经纤维束损害是血管性认知功能损害的主要发病机制,其关键部位在额叶(尤其是前额区)、前扣带回、海马回、下丘脑、基底节、顶叶(特别是优势半球角回)和颞叶等,这些部位多数与小脑存在纤维联系。本文综述了近年来对小脑各部分组件式结构和功能,及其与血管性认知功能损害关系等方面的研究,探讨小脑在血管性认知功能损害中的作用。
小腦不僅與運動有關,而且也參與非運動的認知功能。血管性認知功能障礙是認知功能疾病中的一箇重要分支,其主要與腦血管病危險因素及高齡有關。腦組織缺血導緻的神經細胞及神經纖維束損害是血管性認知功能損害的主要髮病機製,其關鍵部位在額葉(尤其是前額區)、前釦帶迴、海馬迴、下丘腦、基底節、頂葉(特彆是優勢半毬角迴)和顳葉等,這些部位多數與小腦存在纖維聯繫。本文綜述瞭近年來對小腦各部分組件式結構和功能,及其與血管性認知功能損害關繫等方麵的研究,探討小腦在血管性認知功能損害中的作用。
소뇌불부여운동유관,이차야삼여비운동적인지공능。혈관성인지공능장애시인지공능질병중적일개중요분지,기주요여뇌혈관병위험인소급고령유관。뇌조직결혈도치적신경세포급신경섬유속손해시혈관성인지공능손해적주요발병궤제,기관건부위재액협(우기시전액구)、전구대회、해마회、하구뇌、기저절、정협(특별시우세반구각회)화섭협등,저사부위다수여소뇌존재섬유련계。본문종술료근년래대소뇌각부분조건식결구화공능,급기여혈관성인지공능손해관계등방면적연구,탐토소뇌재혈관성인지공능손해중적작용。
The cerebellum is not only associated with the motor, but also the cognitive functions of the non-motor. Vascular cognitive impairment is one of the most important branches among the cognitive function disorder. It has close relations with the risk factors of cerebrovascular disease and old ages. The damage of the nerve cell and nerve ifber bundle caused by cerebral ischemia is the main pathogenesis of vascular cognitive impairment. The strategic positions associated with vascular cognitive impairment include the frontal lobe (especially the prefrontal cortex), anterior cingulate gyrus, hippocampal gyrus, hypothalamus, basal ganglia, parietal lobe (especially the gyrus angular of dominant hemisphere), and temporal cortex, most of which are associated with the cerebellum through the ifbers. This article reviews the recent studies about the modular organization and function of the cerebellum, and its relationships with vascular cognitive impairment, to investigate the role of each anatomic site of the cerebellum on vascular cognitive impairment.