CAJ | 학술논문

目的：归纳总结注射用奥美拉唑钠的配伍禁忌。方法：收集2004～2013年国内公开发表的关于注射用奥美拉唑钠配伍禁忌的文章，进行总结分析。结果：共有73种药物与注射用奥美拉唑钠存在配伍禁忌，配伍使用常出现变色、浑浊、产生沉淀等现象，溶液的pH值、温度、光线等会对奥美拉唑钠溶液的稳定性产生影响。结论：注射用奥美拉唑钠与许多药物存在配伍禁忌，不应与其他药物配伍，临床使用时应选择0.9%氯化钠注射液或生产厂家提供的专用溶剂作溶媒，现配现用，并在12h内滴注完毕。
목적：귀납총결주사용오미랍서납적배오금기。방법：수집2004～2013년국내공개발표적관우주사용오미랍서납배오금기적문장，진행총결분석。결과：공유73충약물여주사용오미랍서납존재배오금기，배오사용상출현변색、혼탁、산생침정등현상，용액적pH치、온도、광선등회대오미랍서납용액적은정성산생영향。결론：주사용오미랍서납여허다약물존재배오금기，불응여기타약물배오，림상사용시응선택0.9%록화납주사액혹생산엄가제공적전용용제작용매，현배현용，병재12h내적주완필。
Objective:To summarize the incompatibility of omeprazole sodium for injection. Methods:Domestic literatures form 2004 to 2013 about incompatibility between omeprazole sodium for injection and other drugs were summarized and analyzed.Results:Omeprazole sodium for injection was incompatible with 88 drugs. Adding other drugs into omeprazole sodium for injection could result in the change of the external appearance of solution.The pH value,temperature and light could affect the stability of omeprazole sodium for injection. Conclusion:Omeprazole sodium for injection is incompatible with many drugs. It should be added into 0.9% NS in clinical infusion, and the infusion should be finished within 12h.