CAJ | 학술논문

目的比较前节光学相干断层扫描（AS-OCT）及超生物显微镜（UBM）所测量眼前房深度结果的差异程度。方法计算机检索相关数据库，搜集关于AS-OCT及UBM测量眼前房深度比较的研究性文献，两名评价员按照纳入排除标准独立对文献进行筛选及质量评价，对最终纳入的文献进行Meta分析。结果共纳入8篇研究文献，合计710眼，Meta分析显示：AS-OCT及UBM在全体人群中测得的前房深度值无统计学意义上的差异[SMD=0.19，95%置信区间为（0.00，0.39）]；在原发性闭角型青光眼患者中测得的前房深度值亦无统计学意义上的差异[SMD=0.02，95%置信区间为（-0.04，0.19）]。结论AS-OCT及UBM所测量的前房深度不存在显著统计学差异，但由于研究文献偏少、样本量较小，致使本系统评价结果论证强度不高，还需要开展更高质量的一致性分析。
목적비교전절광학상간단층소묘（AS-OCT）급초생물현미경（UBM）소측량안전방심도결과적차이정도。방법계산궤검색상관수거고，수집관우AS-OCT급UBM측량안전방심도비교적연구성문헌，량명평개원안조납입배제표준독립대문헌진행사선급질량평개，대최종납입적문헌진행Meta분석。결과공납입8편연구문헌，합계710안，Meta분석현시：AS-OCT급UBM재전체인군중측득적전방심도치무통계학의의상적차이[SMD=0.19，95%치신구간위（0.00，0.39）]；재원발성폐각형청광안환자중측득적전방심도치역무통계학의의상적차이[SMD=0.02，95%치신구간위（-0.04，0.19）]。결론AS-OCT급UBM소측량적전방심도불존재현저통계학차이，단유우연구문헌편소、양본량교소，치사본계통평개결과론증강도불고，환수요개전경고질량적일치성분석。
Objective To compare the differences in the anterior chamber depth (ACD) measured by anterior segment optical coherence tomography (AS-OCT) and ultrasound biomicroscopy (UBM). Methods All studies pertaining to ACD measured by AS-OCT and UBM were collected from online databases. The assessment of methodological quality and data extraction from the included studies were performed independently by two reviewers for meta-analysis. Results Eight studies involving 710 eyes were included in the analysis. The difference of ACD measurements between AS-OCT and UBM was not statistically significant in the overall patients included for analysis (SMD=0.19, 95%CI[0.00, 0.39]) or in the patients with primary angle-closed glaucoma (SMD=0.02,95%CI[-0.04,0.19]). Conclusion The ACD measurements do not differ significantly between AS-OCT and UBM. Due to the relatively small number of the included studies and the patients involved, this conclusion needs further confirmation by high-quality studies involving larger sample sizes.