中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
18期
2786-2788
,共3页
颅脑损伤%免疫,营养%预后
顱腦損傷%免疫,營養%預後
로뇌손상%면역,영양%예후
Craniocerebral trauma%Immunity,nutrition therapy%Prognosis
目的 探讨免疫营养治疗对重型颅脑损伤患者康复的影响.方法 根据营养治疗的不同将80例重型颅脑损伤患者分为对照组和观察组,各40例.两组患者均采用常规治疗,同时观察组给予免疫营养治疗,对照组给予常规营养治疗.观察治疗后第14天、第30天的营养状况,比较治疗3个月后两组患者的Barthel指数、Fugl-Meyer评分和神经功能恢复情况.结果 两组治疗后血浆白蛋白(Alb)和转铁蛋白(TF)显著升高(t=5.75、6.38、1.27、2.63,均P＜0.05)；观察组的ALB和TF在治疗后第14天、第30天均显著高于对照组(t=11.26、6.53、1.27、1.68,均P＜0.05).治疗3个月后两组比较,观察组临床疗效满意率(60.00％)好于对照组(37.50％)(χ2=9.67,P＜0.05),Barthel指数、Fugl-Meyer评分比较差异均有统计学意义(t =3.24、2.88,均P＜0.05).结论 免疫营养治疗可以显著促进重型颅脑损伤患者神经功能恢复,从而改善预后、提高患者的生存质量.
目的 探討免疫營養治療對重型顱腦損傷患者康複的影響.方法 根據營養治療的不同將80例重型顱腦損傷患者分為對照組和觀察組,各40例.兩組患者均採用常規治療,同時觀察組給予免疫營養治療,對照組給予常規營養治療.觀察治療後第14天、第30天的營養狀況,比較治療3箇月後兩組患者的Barthel指數、Fugl-Meyer評分和神經功能恢複情況.結果 兩組治療後血漿白蛋白(Alb)和轉鐵蛋白(TF)顯著升高(t=5.75、6.38、1.27、2.63,均P＜0.05)；觀察組的ALB和TF在治療後第14天、第30天均顯著高于對照組(t=11.26、6.53、1.27、1.68,均P＜0.05).治療3箇月後兩組比較,觀察組臨床療效滿意率(60.00％)好于對照組(37.50％)(χ2=9.67,P＜0.05),Barthel指數、Fugl-Meyer評分比較差異均有統計學意義(t =3.24、2.88,均P＜0.05).結論 免疫營養治療可以顯著促進重型顱腦損傷患者神經功能恢複,從而改善預後、提高患者的生存質量.
목적 탐토면역영양치료대중형로뇌손상환자강복적영향.방법 근거영양치료적불동장80례중형로뇌손상환자분위대조조화관찰조,각40례.량조환자균채용상규치료,동시관찰조급여면역영양치료,대조조급여상규영양치료.관찰치료후제14천、제30천적영양상황,비교치료3개월후량조환자적Barthel지수、Fugl-Meyer평분화신경공능회복정황.결과 량조치료후혈장백단백(Alb)화전철단백(TF)현저승고(t=5.75、6.38、1.27、2.63,균P＜0.05)；관찰조적ALB화TF재치료후제14천、제30천균현저고우대조조(t=11.26、6.53、1.27、1.68,균P＜0.05).치료3개월후량조비교,관찰조림상료효만의솔(60.00％)호우대조조(37.50％)(χ2=9.67,P＜0.05),Barthel지수、Fugl-Meyer평분비교차이균유통계학의의(t =3.24、2.88,균P＜0.05).결론 면역영양치료가이현저촉진중형로뇌손상환자신경공능회복,종이개선예후、제고환자적생존질량.
Objective To explore the influence of immune and nutrition therapy on the rehabilitation of patients with severe traumatic brain injury.Methods According to the different nutritional therapy,80 patients with severe traumatic brain injury were divided into the control group and observation group,each group 40 cases.The patients of the two groups were all given similarly conventional methods,and the observation group were given immune nutrition therapy,the control group were given routine nutrition therapy.After 14d,30d treattnent,nutritional status of the two groups were observed.Barthel Index,Fugl-Meyer score of the two groups of patients and recovery of neurological function were compared 3 months after treatment.Results After treatment,ALB and TF increased significantly (t =5.75,6.38,1.27,2.63,all P ＜ 0.05) ；ALB and TF in the observation group 14 d and 30 d after treatment were significantly higher than those of the control group (t =11.26,6.53,1.27,1.68,all P ＜ 0.05).After 3 months of treatment between the two groups,the clinical efficacy of the observation group was 60.00％,which was better than that of control group(37.50％) (χ2 =9.67,P ＜ 0.05),the differences of Barthel Index and,Fugl-Meyer score were statistically significant (t =3.24,2.88,all P ＜ 0.05).Conclusion The immune and nutritional therapy can significantly promote the neurological function recovery of patients with severe traumatic brain injury,so as to improve the prognosis and the patients's quality of life.
