国际儿科学杂志
國際兒科學雜誌
국제인과학잡지
INTERNATIONAL JOURNAL OF PEDIATRICS
2014年
4期
401-403,404
,共4页
张馨怡(综述)%薛辛东(审校)
張馨怡(綜述)%薛辛東(審校)
장형이(종술)%설신동(심교)
上皮-间质转化%胚胎发育%纤维化疾病%肿瘤
上皮-間質轉化%胚胎髮育%纖維化疾病%腫瘤
상피-간질전화%배태발육%섬유화질병%종류
Epithelial-mesenchymal transition%Embryonic development%Fibrotic disease%Tumor
上皮-间质转化( epithelial-mesenchymal transition,EMT)是指上皮细胞经过转分化变成间质细胞,对其认识最初始于胚胎发育的研究,继而发现在多细胞生物体内的一些生理、病理过程中同样存在EMT现象。近年来与EMT相关的肿瘤浸润和转移、纤维化疾病的发生与发展已成为研究热点。
上皮-間質轉化( epithelial-mesenchymal transition,EMT)是指上皮細胞經過轉分化變成間質細胞,對其認識最初始于胚胎髮育的研究,繼而髮現在多細胞生物體內的一些生理、病理過程中同樣存在EMT現象。近年來與EMT相關的腫瘤浸潤和轉移、纖維化疾病的髮生與髮展已成為研究熱點。
상피-간질전화( epithelial-mesenchymal transition,EMT)시지상피세포경과전분화변성간질세포,대기인식최초시우배태발육적연구,계이발현재다세포생물체내적일사생리、병리과정중동양존재EMT현상。근년래여EMT상관적종류침윤화전이、섬유화질병적발생여발전이성위연구열점。
Epithelial-mesenchymal transition( EMT) refers to the transdifferentiation from epithelial cells to mesenchymal cells. The initial understanding of EMT is originated from the research on embryonic develop-ment,followed by the discovery of EMT phenomenon in physiological and pathological process in multicellular organism. In recent years,the occurrence and development of infiltration and metastasis of tumor cells along with fibrotic diseases that related to EMT are becoming the hot researches nowadays.
