中国生化药物杂志
中國生化藥物雜誌
중국생화약물잡지
CHINESE JOURNAL OF BIOCHEMICAL PHARMACEUTICS
2014年
4期
164-168
,共5页
八正颗粒%栀子苷%大黄素%大黄酚%质量标准
八正顆粒%梔子苷%大黃素%大黃酚%質量標準
팔정과립%치자감%대황소%대황분%질량표준
eight-positive particles%gardenin%emodin%chrysophanol%quality standards
目的：改进八正颗粒的含量测定法，更好地控制药品质量。方法运用高效液相色谱法对八正颗粒中栀子苷、大黄素和大黄酚含量进行测定，拟订含量测定标准，改进和完善质量控制标准。结果新修订的栀子苷、大黄素和大黄酚含量检测方法简单可行，且灵敏度高。结论统一了八正颗粒质量标准，为规范市场中八正颗粒的质量提供了依据。
目的：改進八正顆粒的含量測定法，更好地控製藥品質量。方法運用高效液相色譜法對八正顆粒中梔子苷、大黃素和大黃酚含量進行測定，擬訂含量測定標準，改進和完善質量控製標準。結果新脩訂的梔子苷、大黃素和大黃酚含量檢測方法簡單可行，且靈敏度高。結論統一瞭八正顆粒質量標準，為規範市場中八正顆粒的質量提供瞭依據。
목적：개진팔정과립적함량측정법，경호지공제약품질량。방법운용고효액상색보법대팔정과립중치자감、대황소화대황분함량진행측정，의정함량측정표준，개진화완선질량공제표준。결과신수정적치자감、대황소화대황분함량검측방법간단가행，차령민도고。결론통일료팔정과립질량표준，위규범시장중팔정과립적질량제공료의거。
Objective To improve the content determination of eight-positive particles,and better control drug quality.Methods Gardenin, emodin and chrysophanol of eight-positive particles were determined by HPLC.Revised content determination standards and improved the standards of quality control. Results The revised content determinations of gardenin, emodin and chrysophanol were simple and feasible, and had high sensitivity.Conclusion Unification the quality standards of eight positive granules,the standards provide the basis for standardizing the market of eight-positive particles.
