CAJ | 학술논문

目的：观察红景天注射液在外科高风险手术前的应用效果。方法：将180例普外科高风险手术患者。随机分为3组，红景天组在常规治疗的基础上术前3 d使用红景天注射液，目标导向性治疗（EGDT）组在常规治疗的基础上术前6 h采用EGDT治疗，对照组采用常规治疗。观察各组ScvO2、血乳酸的变化以及术后并发症发生率。结果：红景天组其ScvO2和血乳酸与对照组存在显著性差异（P＜0.01），EGDT组与对照组间的ScvO2和血乳酸也存在显著性差异；红景天组和EGDT组均能降低术后并发症的发生率（P＜0.01），红景天组在降低术后心血管系统并发症上更具优势。结论：红景天注射在高风险手术术前有较好应用前景，可以有效改善机体的缺氧状况，降低术后并发症的发生率。其术前应用的价值可能较EGDT更有优势。
목적：관찰홍경천주사액재외과고풍험수술전적응용효과。방법：장180례보외과고풍험수술환자。수궤분위3조，홍경천조재상규치료적기출상술전3 d사용홍경천주사액，목표도향성치료（EGDT）조재상규치료적기출상술전6 h채용EGDT치료，대조조채용상규치료。관찰각조ScvO2、혈유산적변화이급술후병발증발생솔。결과：홍경천조기ScvO2화혈유산여대조조존재현저성차이（P＜0.01），EGDT조여대조조간적ScvO2화혈유산야존재현저성차이；홍경천조화EGDT조균능강저술후병발증적발생솔（P＜0.01），홍경천조재강저술후심혈관계통병발증상경구우세。결론：홍경천주사재고풍험수술술전유교호응용전경，가이유효개선궤체적결양상황，강저술후병발증적발생솔。기술전응용적개치가능교EGDT경유우세。
Objective To evaluate the efficacy of preoperative use of Rhodiola rosea injection in high-risk surgery. Methods One hundred and 80 cases of high-risk surgical patients admitted were enrolled and ran-domizely divided into three groups. Besides conventional treatment, Rhodiola rosea injection was used 3 days be-fore operation in one group,in another group early goal directed therapy (EGDT) was used 6 hrs before opera-tion. Patients of control group were treated with conventional therapy. ScvO2, lactic acid, SaO2 was measured, and the incidence of postoperative complications was observed and compared. Results After 3 days of using Rhodiola rosea injection, compared with the control group, there were significantly difference on ScvO2 and lac-tic acid either in Rhodiola group or in early goal directed therapy (EGDT) group, while there was no difference between Rhodiola group and EGDT group. All groups had no difference on SaO2. Either Rhodiola group or EGDT group could significantly reduced postoperative complications (P<0.01). Rhodiola group had more advan-tages in the reduction of postoperative complications of cardiovascular system. Conclusion As preoperative treatment of high-risk surgery Rhodiola has good application prospect. It can not only improve hypoxia condi-tion, reduce the incidence of postoperative complications, but also save ICU resource. The preoperative use of Rhodiola may show more advantages than EGDT.