CAJ | 학술논문

目的：了解选择性剖宫产产妇围手术期抗生素使用时机与术后母儿感染的关系。方法将选择性剖宫产产妇1019例，根据不同给药方案分为观察组501例，对照组518例。观察组断脐后5 min用抗生素一剂；对照组在切皮前30 min 开始用抗生素，共用24~48 h。观察两组母儿感染率及抗生素用量。结果观察组和对照组在伤口感染、子宫内膜炎、尿路感染及新生儿黄疸与败血症发生率、入重症监护室率比较，差异无统计学意义（P >0.05）。结论剖宫产预防性应用抗生素的时机并不影响产后感染的发生率，单剂量抗生素能达到预期效果。
목적：료해선택성부궁산산부위수술기항생소사용시궤여술후모인감염적관계。방법장선택성부궁산산부1019례，근거불동급약방안분위관찰조501례，대조조518례。관찰조단제후5 min용항생소일제；대조조재절피전30 min 개시용항생소，공용24~48 h。관찰량조모인감염솔급항생소용량。결과관찰조화대조조재상구감염、자궁내막염、뇨로감염급신생인황달여패혈증발생솔、입중증감호실솔비교，차이무통계학의의（P >0.05）。결론부궁산예방성응용항생소적시궤병불영향산후감염적발생솔，단제량항생소능체도예기효과。
Objective TO study the relatiOnshiP between timing Of PeriOPerative antibiOtics use in selective cesarean sectiOn and POstOPerative infectiOn On maternal and fetus. Methods AccOrding tO the different dOsage regimens,1 019 cases were divided intO twO grOuPs,ObservatiOn grOuP with 501 cases,cOntrOl grOuP with 518 cases. Cases in ObservatiOn grOuP used a dOse Of antibiOtics 5 minutes after OmPhalOtOmy Of neOnates,while cases in cOntrOl grOuP were given antibiOtics 30 minutes befOre skin incisiOn,with a tOtal dasage Of 24 tO 48 hOurs. POstOPerative infectiOn rate and dOsage Of antibiOtics were Observed in twO grOuPs. Results NO significant differences were fOund in wOund infectiOn,endOmetritis,urinary tract infectiOn,neOnatal jaundice and sePticemia,cure rate Of intensive care unit between twO grOuPs(P > 0. 05). Conclusion Different timing Of the PrOPhylactic antibiOtics use in cesarean sectiOn dO nOt change POstPartum infectiOn rate,a single dOse Of antibiOtics can achieve the desired effect.