中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2013年
17期
66-68
,共3页
蚤休%古拉定%妊娠%乙型肝炎%疗效%安全性
蚤休%古拉定%妊娠%乙型肝炎%療效%安全性
조휴%고랍정%임신%을형간염%료효%안전성
Rhizome of Manyleaf Paris%Gluthion%Pregnancy%Hepatitis B%Efficacy%Safety
目的分析探讨蚤休、古拉定治疗妊娠合并乙型肝炎患者的疗效及安全性。方法选取2004年1月～2012年3月在我院诊治的妊娠合并乙型肝炎患者72例，随机分成临床组（蚤休、古拉定）36例，对照组（拉米夫定、古拉定）36例，分析对比两组治疗效果、不良反应，孕妇、胎儿（新生儿）孕围期监测指标。结果临床组治愈24例（66.67%），显效10例（27.78%），好转2例（5.55%）；对照组治愈21例（58.33%），显效13例（36.11%），好转2例（5.55%）。临床组：孕妇及胎儿生理指标正常，足月顺娩，未发现胎儿畸形、缺陷，产后出血2例（5.56%），无一例早产、孕妇围生儿死亡，无其他不良反应和并发症发生。对照组在上述指标中死胎1例（2.78%），早产1例（2.78%），产后出血2例（5.56%）。结论蚤休、古拉定治疗妊娠合并乙型病毒性肝炎临床效果良好，无明显不良反应发生，用药安全。
目的分析探討蚤休、古拉定治療妊娠閤併乙型肝炎患者的療效及安全性。方法選取2004年1月～2012年3月在我院診治的妊娠閤併乙型肝炎患者72例，隨機分成臨床組（蚤休、古拉定）36例，對照組（拉米伕定、古拉定）36例，分析對比兩組治療效果、不良反應，孕婦、胎兒（新生兒）孕圍期鑑測指標。結果臨床組治愈24例（66.67%），顯效10例（27.78%），好轉2例（5.55%）；對照組治愈21例（58.33%），顯效13例（36.11%），好轉2例（5.55%）。臨床組：孕婦及胎兒生理指標正常，足月順娩，未髮現胎兒畸形、缺陷，產後齣血2例（5.56%），無一例早產、孕婦圍生兒死亡，無其他不良反應和併髮癥髮生。對照組在上述指標中死胎1例（2.78%），早產1例（2.78%），產後齣血2例（5.56%）。結論蚤休、古拉定治療妊娠閤併乙型病毒性肝炎臨床效果良好，無明顯不良反應髮生，用藥安全。
목적분석탐토조휴、고랍정치료임신합병을형간염환자적료효급안전성。방법선취2004년1월～2012년3월재아원진치적임신합병을형간염환자72례，수궤분성림상조（조휴、고랍정）36례，대조조（랍미부정、고랍정）36례，분석대비량조치료효과、불량반응，잉부、태인（신생인）잉위기감측지표。결과림상조치유24례（66.67%），현효10례（27.78%），호전2례（5.55%）；대조조치유21례（58.33%），현효13례（36.11%），호전2례（5.55%）。림상조：잉부급태인생리지표정상，족월순면，미발현태인기형、결함，산후출혈2례（5.56%），무일례조산、잉부위생인사망，무기타불량반응화병발증발생。대조조재상술지표중사태1례（2.78%），조산1례（2.78%），산후출혈2례（5.56%）。결론조휴、고랍정치료임신합병을형병독성간염림상효과량호，무명현불량반응발생，용약안전。
Objective To analyze and discuss the efficacy and safety of rhizome of Manyleaf Paris and Gluthion in the treatment of pregnancy complicated with hepatitis B. Methods Seventy-two pregnancy patients with hepatitis B in our hospital from January 2004 to March 2012 were chose, and were randomly divided into 36 cases of clinical group(rhizome of Manyleaf Paris and Gluthion) and 36 cases of control group(lamivudine and Gluthion).The curative effect,adverse reactions,gestational and perinatal monitoring indicators of pregnant women and fetus(neonatal) of two groups were analyzed and compared. Results In the clinical group,24 cases(66.67%) cured,10 cases(27.78%) improved markedly,2 cases(5.55%) improved;In the control group,21 cases(58.33%) cured,13 cases(36.11%) improved markedly,2 cases(5.55%) improved.In the clinical group,the physiological indicators of pregnant women and fetus were normal,the patients were normal spontaneous full-term delivery,fetal abnormalities and defect had not been found,2 cases(5.56%) happened postpartum hemorrhage,no a case of premature birth and death in pregnant women and perinatal happened,and no other adverse reactions and complications happened.In the control group,fetal death occurred in 1 case(2.78%),1 case(2.78%) was premature birth,2 cases(5.56%) were postpartum hemorrhage. Conclusion Rhizome of Manyleaf Paris and Gluthion in the treatment of pregnancy complicated with hepatitis B has good clinical effect,no significant adverse reactions,and is safe.
