CAJ | 학술논문

目的建立开窍醒脑滴鼻剂的含量测定方法。方法采用高效液相色谱法对栀子苷、姜黄素含量进行测定；采用气相色谱法对冰片、麝香酮含量进行测定。结果桅子苷在30～150μg/mL范围内、姜黄素在4～40μg/mL范围内线性关系良好，r≥0.9997（n=7）。麝香酮在0.005～0.25μg/mL范围内、右旋龙脑在0.05～2.56μg/mL范围内线性关系良好，r≥0.9997（n=6）。结论本研究建立的栀子苷、姜黄素、冰片和麝香酮等的含量测定方法灵敏、准确、可靠，且重现性好，可用于开窍醒脑滴鼻剂的含量测定质量控制。
목적건립개규성뇌적비제적함량측정방법。방법채용고효액상색보법대치자감、강황소함량진행측정；채용기상색보법대빙편、사향동함량진행측정。결과외자감재30～150μg/mL범위내、강황소재4～40μg/mL범위내선성관계량호，r≥0.9997（n=7）。사향동재0.005～0.25μg/mL범위내、우선용뇌재0.05～2.56μg/mL범위내선성관계량호，r≥0.9997（n=6）。결론본연구건립적치자감、강황소、빙편화사향동등적함량측정방법령민、준학、가고，차중현성호，가용우개규성뇌적비제적함량측정질량공제。
Objective To establish resuscitation refreshing nasal drops method for the determination. Methods Determination of Jasminoidin and Curcumin in Resuscitation refreshing Nasal drops by HPLC,determination of Borneol and Muscone in Resuscitation refreshing Nasal drops by GC. Results In the examination of Jasminoidin and Curcumin,the calibration curve was linear in the range of 30 ~ 150μg/mL and 4 -40μg/mL,r ≥ 0.9997(n=7). in the examination of Borneol and Muscone, the calibration curve was linear in the range of 0.005-0.25μg/mL and 0.05-2.56μg/ mL,r≥0.9997,n=6). Conclusion Demonstrates that these methods are simple, accurate and reliable and with good reproducibility,which can be used for Resuscitation refreshing Nasal drops quality control.