CAJ | 학술논문

目的探讨预测严重脓毒症患者病情及预后简单易行且有实用价值的指标。方法对72例入住中山市古镇医院ICU严重脓毒症患者入住时作APACHE Ⅱ评分及血乳酸、碱剩余测定，6 h后再次测血乳酸，并计算乳酸清除率，比较不同APACHE Ⅱ评分分值组与血乳酸及乳酸清除率、剩余碱的关系。结果6 h乳酸清除率、碱剩余存活组明显高于死亡组，6 h乳酸清除率及碱剩余与48 hAPACHE Ⅱ评分有相关性。结论乳酸清除率、碱剩余可以作为评估严重脓毒症病情及预后的指标。
목적탐토예측엄중농독증환자병정급예후간단역행차유실용개치적지표。방법대72례입주중산시고진의원ICU엄중농독증환자입주시작APACHE Ⅱ평분급혈유산、감잉여측정，6 h후재차측혈유산，병계산유산청제솔，비교불동APACHE Ⅱ평분분치조여혈유산급유산청제솔、잉여감적관계。결과6 h유산청제솔、감잉여존활조명현고우사망조，6 h유산청제솔급감잉여여48 hAPACHE Ⅱ평분유상관성。결론유산청제솔、감잉여가이작위평고엄중농독증병정급예후적지표。
Objective To investigate the simple and practical target to forecast of the state and prognosis of the patients with severe sepsis. Mathods Detect Lactate and Base Excess of the 72 patients with severe sepsis after admission, in the same time score the patients with acute physiology and chronic health evaluationⅡ(APACHEⅡ), detect Lactate again after 6 hours ,and calculate Lactate Clearance,compare with Lactate, Lactate Clearance and Base Excess in different groups of APACHE Ⅱ.Results 6 hours Lactate Clearance and Base Excess between 2 groups has statistical signiifcation There are relativity between 6 hours Lactate Clearance, Base Excess and APACHEⅡscore in 48 hours. Conclusion Combing Lactate Clearance and Base Excess can evaluate the state and prognosis of the patients with severe sepsis.