CAJ | 학술논문

背景：镁合金作为骨折内固定材料具有力学性能与骨相近、生物相容性好和可降解等突出优点，但其在体液中降解速度过快，成为其临床应用的瓶颈，因此综合利用表面处理提高其耐蚀性能具有重要意义。 　　目的：综合运用磁控溅射技术和碱热处理技术在镁合金表面制备兼具耐蚀性能和生物活性的涂层。 　　方法：首先采用熔炼技术制备Mg-Zn-Mn合金，利用磁控溅射技术在材料表面制备致密涂层，然后利用碱性溶液对表面涂层进行处理，利用模拟体液浸泡实验研究涂层的腐蚀行为，通过表面产物中钙和磷的含量推测涂层的生物活性。 　　结果与结论：经磁控溅射和碱热处理技术在镁合金表面制备兼具耐蚀性能和生物活性的涂层；经模拟体液浸泡24和168 h后涂层表面沉积含Ca，P产物，Ca/P比分别为1.54和2.11，接近类骨磷酸盐Ca/P比，涂层表面的浸泡24 h形成5-10μm点腐蚀，随着浸泡时间增加点腐蚀逐渐长大，浸泡168 h后点腐蚀增加为100-800μm。
배경：미합금작위골절내고정재료구유역학성능여골상근、생물상용성호화가강해등돌출우점，단기재체액중강해속도과쾌，성위기림상응용적병경，인차종합이용표면처리제고기내식성능구유중요의의。 　　목적：종합운용자공천사기술화감열처리기술재미합금표면제비겸구내식성능화생물활성적도층。 　　방법：수선채용용련기술제비Mg-Zn-Mn합금，이용자공천사기술재재료표면제비치밀도층，연후이용감성용액대표면도층진행처리，이용모의체액침포실험연구도층적부식행위，통과표면산물중개화린적함량추측도층적생물활성。 　　결과여결론：경자공천사화감열처리기술재미합금표면제비겸구내식성능화생물활성적도층；경모의체액침포24화168 h후도층표면침적함Ca，P산물，Ca/P비분별위1.54화2.11，접근류골린산염Ca/P비，도층표면적침포24 h형성5-10μm점부식，수착침포시간증가점부식축점장대，침포168 h후점부식증가위100-800μm。
BACKGROUND:Magnesium al oy as a fracture fixation material has mechanical properties similar to the bone, good biocompatibility and biodegradability, but its rapid degradation rate in body fluids becomes a clinical bottleneck. Therefore, the use of surface treatments to improve its corrosion resistance is important. OBJECTIVE:To use magnetron sputtering technology and alkali heat treatment technology in the preparation of coating characterized as both corrosion resistance and biological activity. METHODS:First, we prepared Mg-Zn-Mn al oy using the smelting technology, and prepared a dense coating on the al oy surface by the magnetron sputtering technique. Then, we processed the coating surface using an alkaline solution, and studied the corrosion behavior of the coating by use of simulated body fluid experiments. We speculated the biological activity of the coating by measuring the content of calcium and phosphorus from the surface products. RESULTS AND CONCLUSION:We prepared the coating, which had both corrosion resistance and biological activity, on the surface of magnesium al oy by use of magnetron sputtering and alkali heat treatment technology. After soaking in the simulated body fluid for 24 hours and 168 hours, the deposition of the coating surface contained Ca, P products. Ca/P ratios were 1.54 and 2.11, respectively, closed to the bone-phosphate Ca/P ratio. The coating surface formed 5-10μm pitting after 24 hours of immersion, and the pitting grew up with the immersion time. The pitting was enlarged to 100-800μm after 168 hours.