中国生化药物杂志
中國生化藥物雜誌
중국생화약물잡지
CHINESE JOURNAL OF BIOCHEMICAL PHARMACEUTICS
2014年
4期
155-156,160
,共3页
支气管结核%常规雾化治疗%复方磺胺甲恶唑%联合治疗%临床疗效
支氣管結覈%常規霧化治療%複方磺胺甲噁唑%聯閤治療%臨床療效
지기관결핵%상규무화치료%복방광알갑악서%연합치료%림상료효
bronchial tuberculosis%conventional spray treatment%compound sulfamethoxazole%combination therapy%clinical efficacy
目的：探讨和分析复方磺胺甲恶唑联合常规雾化治疗支气管结核临床疗效。方法选取2012年1月～2013年10月在湖北民族学院附属民大医院接受治疗的支气管结核患者190例为研究对象，随机分成2组（n＝95），对照组行常规雾化治疗，观察组在行雾化治疗的基础上，同时给予复方磺胺甲恶唑治疗，观察和对比2组患者临床治疗效果及不良反应发发生情况。结果持续治疗4～6个月后，观察组治疗显效率为70.5％、总有效率为89.5％，对照组显效率和总有效率分别为48.4％和76.8％，2组显效率和总有效率对比差异显著，均有统计学差异（P＜0.05）；在细菌转阴时间指标上，观察组和对照组转阴时间分别为（2.6±0.9）个月和（4.2±1.1）个月，2组对比，差异显著有统计学意义（P＜0.05）；观察组和对照组不良反应发生率分别为7.4％和11.6％，对比差异不显著。结论应用复方磺胺甲恶唑联合常规雾化治疗支气管结核，疗效快，效果显著，细菌转阴时间短，不良反应低，安全性可靠。
目的：探討和分析複方磺胺甲噁唑聯閤常規霧化治療支氣管結覈臨床療效。方法選取2012年1月～2013年10月在湖北民族學院附屬民大醫院接受治療的支氣管結覈患者190例為研究對象，隨機分成2組（n＝95），對照組行常規霧化治療，觀察組在行霧化治療的基礎上，同時給予複方磺胺甲噁唑治療，觀察和對比2組患者臨床治療效果及不良反應髮髮生情況。結果持續治療4～6箇月後，觀察組治療顯效率為70.5％、總有效率為89.5％，對照組顯效率和總有效率分彆為48.4％和76.8％，2組顯效率和總有效率對比差異顯著，均有統計學差異（P＜0.05）；在細菌轉陰時間指標上，觀察組和對照組轉陰時間分彆為（2.6±0.9）箇月和（4.2±1.1）箇月，2組對比，差異顯著有統計學意義（P＜0.05）；觀察組和對照組不良反應髮生率分彆為7.4％和11.6％，對比差異不顯著。結論應用複方磺胺甲噁唑聯閤常規霧化治療支氣管結覈，療效快，效果顯著，細菌轉陰時間短，不良反應低，安全性可靠。
목적：탐토화분석복방광알갑악서연합상규무화치료지기관결핵림상료효。방법선취2012년1월～2013년10월재호북민족학원부속민대의원접수치료적지기관결핵환자190례위연구대상，수궤분성2조（n＝95），대조조행상규무화치료，관찰조재행무화치료적기출상，동시급여복방광알갑악서치료，관찰화대비2조환자림상치료효과급불량반응발발생정황。결과지속치료4～6개월후，관찰조치료현효솔위70.5％、총유효솔위89.5％，대조조현효솔화총유효솔분별위48.4％화76.8％，2조현효솔화총유효솔대비차이현저，균유통계학차이（P＜0.05）；재세균전음시간지표상，관찰조화대조조전음시간분별위（2.6±0.9）개월화（4.2±1.1）개월，2조대비，차이현저유통계학의의（P＜0.05）；관찰조화대조조불량반응발생솔분별위7.4％화11.6％，대비차이불현저。결론응용복방광알갑악서연합상규무화치료지기관결핵，료효쾌，효과현저，세균전음시간단，불량반응저，안전성가고。
Objective To explore clinical efficacy of compound sulfamethoxazole combined with conventional atomization in treatment of bronchial tuberculosis.Methods 190 cases were selected from January 2012 to October 2013 who diagnosised bronchial tuberculosis treated in minda hospital affiliated of Hubei institute for Nationalities,then the patiens were randomly divided into two groups(n=95 ),the control group underwent conventional spray treatment,the observation group row treatment on the basis of atomization,while giving sulfamethoxazole treatment,observation and comparison of two groups clinical outcomes and adverse reactions. Result After continuous treatment for 4~6 months in the observation group therapy effective rate of 70.5%,total effective rate was 89.5%in the control group significant efficiency and total efficiency of 48.4%and 76.8%,respectively,two groups of significant efficiency and total efficiency,there were significant differences(P<0.05 );bacterial turn negative time indicator on the observation group and the control group were respectively(2.6 ±0.9)months and(4.2 ±1.1)months,there was significant difference(P<0.05);adverse reactions in observation group and control group was 7.4% and 11.6%,respectively,which compared no significant difference.Conclusion Application of compound sulfamethoxazole combined with conventional atomization in treatment of bronchial tuberculosis,has quickly and significantly effect,and bacterial clearance time is short,with low adverse reactions,safety and reliable.
