中国生化药物杂志
中國生化藥物雜誌
중국생화약물잡지
CHINESE JOURNAL OF BIOCHEMICAL PHARMACEUTICS
2014年
4期
111-112,115
,共3页
子宫肌瘤%米非司酮%宫瘤消胶囊%联合治疗
子宮肌瘤%米非司酮%宮瘤消膠囊%聯閤治療
자궁기류%미비사동%궁류소효낭%연합치료
uterine fibroids%mifepristone%Gongliuxiao capsule%combination treatment
目的：对单独使用米非司酮及与宫瘤消胶囊合用在子宫肌瘤的临床治疗中所具有的临床效果进行研究。方法选取哈励逊国际和平医院2012年12月～2013年12月期间106例子宫肌瘤患者作为实验组研究对象，将患者随机分为对照组和实验组（n＝53），前者单独使用米非司酮进行治疗，后者使用米非司酮和宫瘤消胶囊联合法进行治疗。治疗周期为24周，12周为一个疗程。对患者治疗前后的月经期、经血量、子宫和子宫肌瘤体积进行检查记录，并对2组的临床治疗效果进行评估对比。结果治疗后2组的月经期、经血量、子宫和子宫肌瘤体积均明显减小，临床效果显著（P＜0.05）。实验组的上述4个指标均显著小于对照组，其临床效果评估总有效率为92.45％，优于对照组的73.58％（P＜0.05）。2组均有轻微不良反应，对治疗和恢复无影响。结论米非司酮和宫瘤消胶囊的联合使用在子宫肌瘤的治疗中效果显著。相比于单独使用米非司酮，其临床效果更为显著。
目的：對單獨使用米非司酮及與宮瘤消膠囊閤用在子宮肌瘤的臨床治療中所具有的臨床效果進行研究。方法選取哈勵遜國際和平醫院2012年12月～2013年12月期間106例子宮肌瘤患者作為實驗組研究對象，將患者隨機分為對照組和實驗組（n＝53），前者單獨使用米非司酮進行治療，後者使用米非司酮和宮瘤消膠囊聯閤法進行治療。治療週期為24週，12週為一箇療程。對患者治療前後的月經期、經血量、子宮和子宮肌瘤體積進行檢查記錄，併對2組的臨床治療效果進行評估對比。結果治療後2組的月經期、經血量、子宮和子宮肌瘤體積均明顯減小，臨床效果顯著（P＜0.05）。實驗組的上述4箇指標均顯著小于對照組，其臨床效果評估總有效率為92.45％，優于對照組的73.58％（P＜0.05）。2組均有輕微不良反應，對治療和恢複無影響。結論米非司酮和宮瘤消膠囊的聯閤使用在子宮肌瘤的治療中效果顯著。相比于單獨使用米非司酮，其臨床效果更為顯著。
목적：대단독사용미비사동급여궁류소효낭합용재자궁기류적림상치료중소구유적림상효과진행연구。방법선취합려손국제화평의원2012년12월～2013년12월기간106례자궁기류환자작위실험조연구대상，장환자수궤분위대조조화실험조（n＝53），전자단독사용미비사동진행치료，후자사용미비사동화궁류소효낭연합법진행치료。치료주기위24주，12주위일개료정。대환자치료전후적월경기、경혈량、자궁화자궁기류체적진행검사기록，병대2조적림상치료효과진행평고대비。결과치료후2조적월경기、경혈량、자궁화자궁기류체적균명현감소，림상효과현저（P＜0.05）。실험조적상술4개지표균현저소우대조조，기림상효과평고총유효솔위92.45％，우우대조조적73.58％（P＜0.05）。2조균유경미불량반응，대치료화회복무영향。결론미비사동화궁류소효낭적연합사용재자궁기류적치료중효과현저。상비우단독사용미비사동，기림상효과경위현저。
Objective To investigate and compare the clinical efficacy of mifepristone alone and combined with Gongliuxiao capsule in the treatment of uterine fibroids.Methods 106 patients with uterine fibroids in Harrison International Peace Hospital from December 2012 to December 2013 were selected.The patients were randomly divided into control group and experimental group(n=53).The former were treated with mifepristone alone while the later were treated with the combination of mifepristone and Gongliuxiao capsule.All the patients were given 2 courses of treatment with 12 weeks for a course.The menstrual phase,volume of menstruation,uterus and the volorne of uterine fibroids before and after the treatment,and the clinical efficacy of both groups were evaluated.All the results were recorded and compared. Results The menstrual phase,volume of menstruation,uterus and uterine fibroids of both groups after the treatment were significantly less than those before treatment (P <0.05 ).And the total effective rate of experimental group was 92.45%,which was significantly higher than 73.58% of control group.Both groups had some mild adverse reactions,which didn’t affect the treatment.Conclusion The combination of mifepristone and Gongliuxiao capsule has a great efficacy in the treatment of uterine fibroids.Compared with the use of mifepristone alone,the combination treatment is much more effective.
