CAJ | 학술논문

目的：观察腮腺主导管结扎及再通后腺体的组织学变化。方法：结扎大鼠右侧腮腺主导管，于结扎后第14天使其再通，分别于再通后第0、1、3、5、7、10、14、21天获取腮腺标本（n＝5），应用HE染色和形态计量方法，观察主导管再通后腺泡、导管及间质的形态及体积分数变化。结果：腮腺组织于主导管结扎后第14天显著萎缩；再通后第3天开始，腺泡体积分数逐渐增多，导管及间质体积分数逐渐减少（P＜0．05）；再通14 d后，腺泡、导管及间质所占体积分数均与正常对照组无显著差异（P＞0．05）。结论：腮腺主导管结扎14 d再通后萎缩的腺体能够再生、恢复正常。
목적：관찰시선주도관결찰급재통후선체적조직학변화。방법：결찰대서우측시선주도관，우결찰후제14천사기재통，분별우재통후제0、1、3、5、7、10、14、21천획취시선표본（n＝5），응용HE염색화형태계량방법，관찰주도관재통후선포、도관급간질적형태급체적분수변화。결과：시선조직우주도관결찰후제14천현저위축；재통후제3천개시，선포체적분수축점증다，도관급간질체적분수축점감소（P＜0．05）；재통14 d후，선포、도관급간질소점체적분수균여정상대조조무현저차이（P＞0．05）。결론：시선주도관결찰14 d재통후위축적선체능구재생、회복정상。
Objective:To investigate the histological changes of parotid gland after ligation and reopening of the main duct.Meth-ods:The right parotid main duct was ligated for 14 days and then reopened,the specimen were harvested at day 0,1,3,5,7,10,14 and 21 after reopening(n=5 )respectively.By HE staining and Morphology measurement,the morphological and volume fraction changes of acinus,duct and mesenchyma were observed and measured.Results:The parotid gland atrophied significantly 14 days af-ter the duct ligation.From day 3 after duct reopening,the acinar volume fraction continued to increase,both the duct and the mesen-chymal tissue volume fraction continued to decrease significantly(P<0.05).After 14 days of duct reopening,there was no signifi-cant difference in volume fraction of acinar,duct and mesenchyma,compared with those of normal control group(P>0.05).Conclu-sion:After reopening of the ligated main duct the atrophied parotid gland is able to regenerate to be normal.