中国医师杂志
中國醫師雜誌
중국의사잡지
JOURNAL OF CHINESE PHYSICIAN
2014年
7期
913-915,918
,共4页
儿童%肠道病毒感染%实验室技术和方法%天冬氨酸氨基转移酶类%肌钙蛋白I%白细胞计数%C反应蛋白质%预后
兒童%腸道病毒感染%實驗室技術和方法%天鼕氨痠氨基轉移酶類%肌鈣蛋白I%白細胞計數%C反應蛋白質%預後
인동%장도병독감염%실험실기술화방법%천동안산안기전이매류%기개단백I%백세포계수%C반응단백질%예후
Child%Enterovirus infections%Laboratory techniques and procedures%Aspartate aminotransferases%Troponin I%Leukocyte count%C-reactive protein%Prognosis
目的：探讨重症肠道病毒感染患儿实验室检查结果的变化是否与预后相关，为重症患儿的早期诊疗提供依据。方法以湖南省儿童医院自2010年1月6日至2010年11月25日收治重症监护室的重症肠道病毒感染病例为研究对象，搜集、调查其相关资料。采用描述性分析、χ2检验、Fisher＇s精确概率法、二分类非条件的Logistic多元分析等方法对资料进行统计学分析。结果33.1％的重症肠道病毒感染患儿会出现白细胞异常，而且1岁以下和5岁以上患儿白细胞异常率高于1～5岁组，差异有统计学意义（χ2＝12.13， P ＜0.01）。天冬氨酸氨基转移酶（AST）和肌钙蛋白I（cTnT）的异常率分别为23.8％和31.5％，52.9％的患儿的CD4淋巴细胞出现减少；WBC、C反应蛋白（ CRP）是否异常与预后之间无关（ P ＞0.05）；降钙素原（ PCT）、AST、cTnT异常与预后之间有关（ P ＜0.01或P ＜0.05）。结论 PCT、AST及cTnT异常与重症肠道病毒感染患儿预后有关，而WBC、CRP异常与预后无关
目的：探討重癥腸道病毒感染患兒實驗室檢查結果的變化是否與預後相關，為重癥患兒的早期診療提供依據。方法以湖南省兒童醫院自2010年1月6日至2010年11月25日收治重癥鑑護室的重癥腸道病毒感染病例為研究對象，搜集、調查其相關資料。採用描述性分析、χ2檢驗、Fisher＇s精確概率法、二分類非條件的Logistic多元分析等方法對資料進行統計學分析。結果33.1％的重癥腸道病毒感染患兒會齣現白細胞異常，而且1歲以下和5歲以上患兒白細胞異常率高于1～5歲組，差異有統計學意義（χ2＝12.13， P ＜0.01）。天鼕氨痠氨基轉移酶（AST）和肌鈣蛋白I（cTnT）的異常率分彆為23.8％和31.5％，52.9％的患兒的CD4淋巴細胞齣現減少；WBC、C反應蛋白（ CRP）是否異常與預後之間無關（ P ＞0.05）；降鈣素原（ PCT）、AST、cTnT異常與預後之間有關（ P ＜0.01或P ＜0.05）。結論 PCT、AST及cTnT異常與重癥腸道病毒感染患兒預後有關，而WBC、CRP異常與預後無關
목적：탐토중증장도병독감염환인실험실검사결과적변화시부여예후상관，위중증환인적조기진료제공의거。방법이호남성인동의원자2010년1월6일지2010년11월25일수치중증감호실적중증장도병독감염병례위연구대상，수집、조사기상관자료。채용묘술성분석、χ2검험、Fisher＇s정학개솔법、이분류비조건적Logistic다원분석등방법대자료진행통계학분석。결과33.1％적중증장도병독감염환인회출현백세포이상，이차1세이하화5세이상환인백세포이상솔고우1～5세조，차이유통계학의의（χ2＝12.13， P ＜0.01）。천동안산안기전이매（AST）화기개단백I（cTnT）적이상솔분별위23.8％화31.5％，52.9％적환인적CD4림파세포출현감소；WBC、C반응단백（ CRP）시부이상여예후지간무관（ P ＞0.05）；강개소원（ PCT）、AST、cTnT이상여예후지간유관（ P ＜0.01혹P ＜0.05）。결론 PCT、AST급cTnT이상여중증장도병독감염환인예후유관，이WBC、CRP이상여예후무관
Objective To explore the clinical characteristic of lab results and prognosis of severe intestinal virus infection dis -ease and to provide the objective basis for early intervention .Methods All children who were admitted in pediatric intensive care unit ( PICU) by laboratory diagnosis as cases of severe intestinal virus infection disease in Hunan Children 's Hospital from January 6 to No-vember 25, 2010 were selected as cases of this study .Their medical records were collected .The data was analyzed by χ2 test, Fisher's exact test , and binary logistic regression .Results A percentage ( 33.1%) of patients had abnormal white blood cell ( WBC ) counts, and the difference rates of younger group (under 1 year old) and upper 5 years old group were higher than that in 1~5 years old group with statistically significance (χ2 =12.13, P <0.01).The difference rates of aspartate aminotransferase (AST) and cardiac troponin I(cTnT) were 23.8%and 31.5%, respectively.A percentage (52.9%) of patients had reduced CD4 lymphocytes.Abnor-mal WBC, C reactive protein (CRP), and prognosis have no significant difference ( P >0.05).There were statistically significant differences in procalcitonin (PCT), AST, cTnT anomalies and prognosis ( P <0.01 or P <0.05).Conclusions Abnormal PCT, AST and cTnT are associated with the prognosis of children with severe intestinal virus infection , while WBC and CRP are not .
