中国保健营养（中旬刊）
中國保健營養（中旬刊）
중국보건영양（중순간）
China Hwalth Care & nutrition
2014年
7期
4146-4147,4148
,共3页
精神分裂症%非酒精性脂肪肝%危险因素%临床分析
精神分裂癥%非酒精性脂肪肝%危險因素%臨床分析
정신분렬증%비주정성지방간%위험인소%림상분석
Schizophrenia%non-alcoholic faty liver disease%risk factors%clinical analysis
目的：了解住院精神分裂症患者非酒精性脂肪肝的患病率及相关危险因素。方法：对150例住院精神分裂症作了体重指数（BMI）、血压、肝胆B超、血糖、血脂、肝功能及尿酸等检测。结果：精神分裂症伴发非酒精性脂肪肝的占34%，其BMI、腰围、臀围、血压明显高于不伴有脂肪肝者（P<0.05），而除载脂蛋白A (ApoA1)、碱性磷酸酶（AKP）外,其他血脂、肝功能指标、血糖、尿酸均与不伴脂肪肝者差异显著（P<0.05）；长期吸烟者与脂肪肝的发生呈一定正相关（P<0.05）；而与药物之间的比较并无显著性差异（P>0.05）。肥胖、糖尿病、血脂异常、吸烟与患脂肪肝有关(回归系数分别为：2.642，2.412，1.406，-2.237)。结论：长期住院的慢性精神分裂症患者伴发非酒精性脂肪肝的比例增高，肥胖、糖尿病、血脂异常、吸烟等是脂肪肝的伴发因素和心血管疾病的危险因素，值得临床关注。
目的：瞭解住院精神分裂癥患者非酒精性脂肪肝的患病率及相關危險因素。方法：對150例住院精神分裂癥作瞭體重指數（BMI）、血壓、肝膽B超、血糖、血脂、肝功能及尿痠等檢測。結果：精神分裂癥伴髮非酒精性脂肪肝的佔34%，其BMI、腰圍、臀圍、血壓明顯高于不伴有脂肪肝者（P<0.05），而除載脂蛋白A (ApoA1)、堿性燐痠酶（AKP）外,其他血脂、肝功能指標、血糖、尿痠均與不伴脂肪肝者差異顯著（P<0.05）；長期吸煙者與脂肪肝的髮生呈一定正相關（P<0.05）；而與藥物之間的比較併無顯著性差異（P>0.05）。肥胖、糖尿病、血脂異常、吸煙與患脂肪肝有關(迴歸繫數分彆為：2.642，2.412，1.406，-2.237)。結論：長期住院的慢性精神分裂癥患者伴髮非酒精性脂肪肝的比例增高，肥胖、糖尿病、血脂異常、吸煙等是脂肪肝的伴髮因素和心血管疾病的危險因素，值得臨床關註。
목적：료해주원정신분렬증환자비주정성지방간적환병솔급상관위험인소。방법：대150례주원정신분렬증작료체중지수（BMI）、혈압、간담B초、혈당、혈지、간공능급뇨산등검측。결과：정신분렬증반발비주정성지방간적점34%，기BMI、요위、둔위、혈압명현고우불반유지방간자（P<0.05），이제재지단백A (ApoA1)、감성린산매（AKP）외,기타혈지、간공능지표、혈당、뇨산균여불반지방간자차이현저（P<0.05）；장기흡연자여지방간적발생정일정정상관（P<0.05）；이여약물지간적비교병무현저성차이（P>0.05）。비반、당뇨병、혈지이상、흡연여환지방간유관(회귀계수분별위：2.642，2.412，1.406，-2.237)。결론：장기주원적만성정신분렬증환자반발비주정성지방간적비례증고，비반、당뇨병、혈지이상、흡연등시지방간적반발인소화심혈관질병적위험인소，치득림상관주。
Objectve:To investigate the prevalence of non-alcoholic faty liver in schizophrenic inpatients and its related risk factors.Methods:150 schizophrenia inpatients treated in Shanghai Mental Health Center received body mass index (BMI),blood pressure and ultrasonography of liver.Serum level of several biochemical materials were measured, which including fasting blood glucose,blood fat,liver function and uric acid.Results:The prevalence of non-alcoholic faty liver in schizophrenic inpatients was 34%,the BMI,waist circumference,hip circumference and blood pressure were significantly higher than those without faty liver(P<0.05);in addition to apolipoprotein A (ApoA1),alkaline phosphatase (AKP) than other blood fat,liver function,blood glucose and uric acid were not associated with faty liver were significantly different(P <0.05);Long-term smokers seem to show a positive correlation with the occurrence of faty liver (P <0.05);the comparison is no significant difference between the drug (P> 0.05).Obesity,diabetes, dyslipidemia,smoking is associated with risk of faty liver (withβ of 2.642,2.412,1.406 and -2.237 respectively).Conclusion:Non-alcoholic faty liver occures in many schizophrenia inpatients,obesity,diabetes, dyslipidemia and smoking is a faty liver with factors and a risk factor for cardiovascular disease.Much atention should be paid even in the early course of ilness.
