CAJ | 학술논문

目的：探讨手足口病（HFMD）对儿童心肌的影响。方法：对89例住院的手足口病患儿和健康查体儿童90例，行肌酸激酶同工酶（CK-MB）、心电图和心脏肌钙蛋白I（cTnI）检查。结果：HFMD患儿与对照组比较，CK-MB及cTnI的水平及异常率明显升高（P＜0.01）；HFMD患儿心电图异常率73.0％，ST-T改变为主要表现；HFMD患儿CK-MB与cTnI呈正相关。结论：手足口病易致患儿心肌损伤，心肌酶谱和cTnI明显升高。心电图多出现异常改变。早期检测血清心肌酶、cTnI水平结合心电图检查可以较好判断HFMD患儿的心肌损害程度，并为临床早期诊断和治疗提供依据。
목적：탐토수족구병（HFMD）대인동심기적영향。방법：대89례주원적수족구병환인화건강사체인동90례，행기산격매동공매（CK-MB）、심전도화심장기개단백I（cTnI）검사。결과：HFMD환인여대조조비교，CK-MB급cTnI적수평급이상솔명현승고（P＜0.01）；HFMD환인심전도이상솔73.0％，ST-T개변위주요표현；HFMD환인CK-MB여cTnI정정상관。결론：수족구병역치환인심기손상，심기매보화cTnI명현승고。심전도다출현이상개변。조기검측혈청심기매、cTnI수평결합심전도검사가이교호판단HFMD환인적심기손해정도，병위림상조기진단화치료제공의거。
To explore the effect of Hand-Foot-Mouth Disease(HFMD) on myocard of children.Methods:we have examined and recorded myocardial enzymes, eletrocarclogram and cTnI in 89 children cases with HFMD,and in 90 cases of children in depantment of childen health care over the same period.Results:The levels and abnormality rate of myocardial enzymes and cTnI in serum were increased in children with HFMD than those in controls(P<0.01); The abnormality rate of ECG in the children with HFMD was 73.0%, ST-T changes was the main abnormality; Partial correlation analysis indicates that CK-MB positively correlated to cTnI.Conclusion:The myocardial damage occurs easly in children with HFMD. myocardial enzymes and cTnI were significantly increased. Most of the ECG abnomal changes. Measuring of myocardial enzyme, cTnI and ECG in early stage can be wel judged the extent of myocardial damage in children with HFMD, and it’s could provide the basis for early clinical diagnosis and therapy.