CAJ | 학술논문

目的：观察益气养阴法联合胰岛素救治糖尿病酮症酸中毒（ DKA）对临床疗效、血糖达标时间、酮体转阴时间、酸中毒纠正所需时间及胰岛素平均日用量的影响。方法将67例DKA患者分为对照组32例，予以微量注射泵持续静脉输注胰岛素及积极补液，补钾、维持水电解质和酸碱平衡等对症治疗；观察组35例，在对照组的基础上予以益气养阴为主的中药口服。观察两组治疗后的临床疗效、血糖达标时间、酮体转阴时间、酸中毒纠正所需时间、胰岛素平均日用量及人均低血糖次数，并对结果进行比较分析。结果观察组能更快控制血糖，明显缩短尿酮转阴及纠正酸中毒所需时间，减少胰岛素用量及人均低血糖次数，与对照组比较有显著差异性（ p＜0.01）；在临床疗效方面，观察组显效19例，有效14例，无效2例，有效率94．29％；对照组显效13例，有效10例，无效9例，有效率71．88％。两组比较显著性差异（p＜0.05）。结论益气养阴法可明显提高治疗DKA的疗效。
목적：관찰익기양음법연합이도소구치당뇨병동증산중독（ DKA）대림상료효、혈당체표시간、동체전음시간、산중독규정소수시간급이도소평균일용량적영향。방법장67례DKA환자분위대조조32례，여이미량주사빙지속정맥수주이도소급적겁보액，보갑、유지수전해질화산감평형등대증치료；관찰조35례，재대조조적기출상여이익기양음위주적중약구복。관찰량조치료후적림상료효、혈당체표시간、동체전음시간、산중독규정소수시간、이도소평균일용량급인균저혈당차수，병대결과진행비교분석。결과관찰조능경쾌공제혈당，명현축단뇨동전음급규정산중독소수시간，감소이도소용량급인균저혈당차수，여대조조비교유현저차이성（ p＜0.01）；재림상료효방면，관찰조현효19례，유효14례，무효2례，유효솔94．29％；대조조현효13례，유효10례，무효9례，유효솔71．88％。량조비교현저성차이（p＜0.05）。결론익기양음법가명현제고치료DKA적료효。
Objective To observe the clinical effect , blood glucose time , clearance time of ketone body , correction time of acidosis and influence on average daily dosage of insulin of supplementing Qi and nourishing Yin combined with insulin treatment of patients with diabetic ketoacidosis (DKA).Methods 67 cases of DKA were divided into 2 groups.Control group (n=32) was giv-en micro injection of pump continuous infusion of insulin and aggressive fluid resuscitation for potassium supplement , water and elec-trolyte maintaining and acid -base balance;the observation group ( n=35 ) was given oral Chinese medicine for supplementing Qi and nourishing Yin on the basis of control group .The clinical effect after treatment , blood glucose time , clearance time of ketone body, correction time of acidosis , average daily dosage of insulin and the average number of hypoglycemia per capita were compared and analyzed .Results Blood sugar could be controlled faster in observation group .Clearance time of urine ketone and correction time of acidosis were significantly shortened .The dosage of insulin and number of hypoglycemia per capita were greatly reduced .There were significant differences compared with the control group (p<0.01);in terms of clinical effect, 19 cases of observation group were markedly effective , 14 cases effective , and 2 cases ineffective with the efficiency rate of 94.29%; 13 cases of control group were markedly effective , 10 cases effective , and 9 cases ineffective with the efficiency rate of 71.88%.There were differences between the two groups (p<0.05).Conclusion Supplementing Qi and nourishing Yin can significantly improve the curative effect in the treat -ment of DKA .